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1. (WO2007011044) PHARMACEUTICAL COMPOSITION COMPRISING DISULFIDE-LINKED HLA-G DIMER AND PROCESS FOR PRODUCTION OF DISULFIDE-LINKED HLA-G DIMER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/011044    International Application No.:    PCT/JP2006/314537
Publication Date: 25.01.2007 International Filing Date: 18.07.2006
IPC:
A61K 39/00 (2006.01), A61P 37/06 (2006.01), A61P 37/08 (2006.01), C07K 14/74 (2006.01)
Applicants: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION [JP/JP]; 10-1, Hakozaki 6-chome, Higashi-ku, Fukuoka-shi, Fukuoka 8128581 (JP) (For All Designated States Except US).
OSAKA UNIVERSITY [JP/JP]; 1-1, Yamadaoka, Suita-shi, Osaka 5650871 (JP) (For All Designated States Except US).
MAENAKA, Katsumi [JP/JP]; (JP) (For US Only).
SHIROISHI, Mitsunori [JP/JP]; (JP) (For US Only).
KOHDA, Daisuke [JP/JP]; (JP) (For US Only).
KUROKI, Kimiko [JP/JP]; (JP) (For US Only).
RASUBALA, Linda [ID/JP]; (JP) (For US Only).
ARASE, Hisashi [JP/JP]; (JP) (For US Only)
Inventors: MAENAKA, Katsumi; (JP).
SHIROISHI, Mitsunori; (JP).
KOHDA, Daisuke; (JP).
KUROKI, Kimiko; (JP).
RASUBALA, Linda; (JP).
ARASE, Hisashi; (JP)
Agent: KOBAYASHI, Hiroshi; c/o ABE, IKUBO & KATAYAMA, Fukuoka Bldg. 9th Fl., 8-7, Yaesu 2-chome Chuo-ku,Tokyo 1040028 (JP)
Priority Data:
60/699,783 15.07.2005 US
Title (EN) PHARMACEUTICAL COMPOSITION COMPRISING DISULFIDE-LINKED HLA-G DIMER AND PROCESS FOR PRODUCTION OF DISULFIDE-LINKED HLA-G DIMER
(FR) COMPOSITION PHARMACEUTIQUE COMPRENANT UN DIMERE HLA-G LIE DISULFIDE ET PROCEDE DE FABRICATION DE CE DIMERE HLA-G LIE DISULFIDE
(JA) ジスルフィド結合型HLA-G二量体を含む医薬組成物及びジスルフィド結合型HLA-G二量体の製造方法
Abstract: front page image
(EN)Disclosed is novel use of an HLA-G dimer. Also disclosed is a process for producing an HLA-G dimer with high efficiency. A pharmaceutical composition comprising an HLA-G dimer; and a process for producing an HLA-G dimer comprising the step of adding a reducing agent to a solution containing HLA-G.
(FR)L'invention concerne une nouvelle utilisation d'un dimère HLA-G. L'invention concerne également un procédé de fabrication très efficace d'un dimère HLA-G. L'invention concerne donc une composition pharmaceutique comprenant un dimère HLA-G ; et un procédé de fabrication d'un dimère HLA-G comprenant une étape d'ajout d'un agent réducteur à une solution contenant HLA-G.
(JA)本発明は、HLA-G二量体の新規用途を提供する。また、HLA-G二量体の効率的な製造方法を提供することにある。本発明の医薬組成物は、HLA-G二量体を含むことを特徴とする。本発明のHLA-G二量体の製造方法は、HLA-Gを含む溶液中に還元剤を添加することを特徴とする。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)