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1. (WO2007011044) PHARMACEUTICAL COMPOSITION COMPRISING DISULFIDE-LINKED HLA-G DIMER AND PROCESS FOR PRODUCTION OF DISULFIDE-LINKED HLA-G DIMER
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/011044 International Application No.: PCT/JP2006/314537
Publication Date: 25.01.2007 International Filing Date: 18.07.2006
IPC:
A61K 39/00 (2006.01) ,A61P 37/06 (2006.01) ,A61P 37/08 (2006.01) ,C07K 14/74 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
06
Immunosuppressants, e.g. drugs for graft rejection
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
08
Antiallergic agents
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
74
Major histocompatibility complex (MHC)
Applicants:
国立大学法人九州大学 KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION [JP/JP]; 〒8128581 福岡県福岡市東区箱崎六丁目10番1号 Fukuoka 10-1, Hakozaki 6-chome, Higashi-ku, Fukuoka-shi, Fukuoka 8128581, JP (AllExceptUS)
国立大学法人大阪大学 OSAKA UNIVERSITY [JP/JP]; 〒5650871 大阪府吹田市山田丘1番1号 Osaka 1-1, Yamadaoka, Suita-shi, Osaka 5650871, JP (AllExceptUS)
前仲 勝実 MAENAKA, Katsumi [JP/JP]; JP (UsOnly)
白石 充典 SHIROISHI, Mitsunori [JP/JP]; JP (UsOnly)
神田 大輔 KOHDA, Daisuke [JP/JP]; JP (UsOnly)
黒木 喜美子 KUROKI, Kimiko [JP/JP]; JP (UsOnly)
ラスバラ リンダ RASUBALA, Linda [ID/JP]; JP (UsOnly)
荒瀬 尚 ARASE, Hisashi [JP/JP]; JP (UsOnly)
Inventors:
前仲 勝実 MAENAKA, Katsumi; JP
白石 充典 SHIROISHI, Mitsunori; JP
神田 大輔 KOHDA, Daisuke; JP
黒木 喜美子 KUROKI, Kimiko; JP
ラスバラ リンダ RASUBALA, Linda; JP
荒瀬 尚 ARASE, Hisashi; JP
Agent:
小林 浩 KOBAYASHI, Hiroshi; 〒1040028 東京都中央区八重洲二丁目8番7号 福岡ビル9階 阿部・井窪・片山法律事務所 Tokyo c/o ABE, IKUBO & KATAYAMA, Fukuoka Bldg. 9th Fl., 8-7, Yaesu 2-chome Chuo-ku,Tokyo 1040028, JP
Priority Data:
60/699,78315.07.2005US
Title (EN) PHARMACEUTICAL COMPOSITION COMPRISING DISULFIDE-LINKED HLA-G DIMER AND PROCESS FOR PRODUCTION OF DISULFIDE-LINKED HLA-G DIMER
(FR) COMPOSITION PHARMACEUTIQUE COMPRENANT UN DIMERE HLA-G LIE DISULFIDE ET PROCEDE DE FABRICATION DE CE DIMERE HLA-G LIE DISULFIDE
(JA) ジスルフィド結合型HLA-G二量体を含む医薬組成物及びジスルフィド結合型HLA-G二量体の製造方法
Abstract:
(EN) Disclosed is novel use of an HLA-G dimer. Also disclosed is a process for producing an HLA-G dimer with high efficiency. A pharmaceutical composition comprising an HLA-G dimer; and a process for producing an HLA-G dimer comprising the step of adding a reducing agent to a solution containing HLA-G.
(FR) L'invention concerne une nouvelle utilisation d'un dimère HLA-G. L'invention concerne également un procédé de fabrication très efficace d'un dimère HLA-G. L'invention concerne donc une composition pharmaceutique comprenant un dimère HLA-G ; et un procédé de fabrication d'un dimère HLA-G comprenant une étape d'ajout d'un agent réducteur à une solution contenant HLA-G.
(JA) 本発明は、HLA-G二量体の新規用途を提供する。また、HLA-G二量体の効率的な製造方法を提供することにある。本発明の医薬組成物は、HLA-G二量体を含むことを特徴とする。本発明のHLA-G二量体の製造方法は、HLA-Gを含む溶液中に還元剤を添加することを特徴とする。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)