WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |

Search International and National Patent Collections
World Intellectual Property Organization
Machine translation
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/011018    International Application No.:    PCT/JP2006/314467
Publication Date: 25.01.2007 International Filing Date: 21.07.2006
A61K 9/20 (2006.01), A61K 31/4545 (2006.01), A61K 47/10 (2006.01), A61K 47/18 (2006.01), A61K 47/22 (2006.01), A61K 47/26 (2006.01), A61K 47/34 (2006.01), A61K 47/36 (2006.01), A61K 47/38 (2006.01), A61K 47/42 (2006.01), A61K 47/44 (2006.01), A61K 47/46 (2006.01), A61P 37/08 (2006.01)
Applicants: MITSUBISHI TANABE PHARMA CORPORATION [JP/JP]; 2-10, Dosho-machi 3-chome, Chuo-ku, Osaka-shi, Osaka 5418505 (JP) (For All Designated States Except US).
UEMURA, Katsuji; (For US Only).
SUGIMOTO, Masaaki; (For US Only).
TAKATSUKA, Shinya; (For US Only).
KOMORI, Toshinobu; (For US Only)
Inventors: UEMURA, Katsuji; .
SUGIMOTO, Masaaki; .
TAKATSUKA, Shinya; .
KOMORI, Toshinobu;
Agent: TSUKUNI, Hajime; SVAX TS Bldg., 22-12, Toranomon 1-chome, Minato-ku, Tokyo 1050001 (JP)
Priority Data:
2005-212836 22.07.2005 JP
(JA) 口腔内速崩壊性錠
Abstract: front page image
(EN)Disclosed is a method for reducing the bitterness of a bitter substance contained in a rapidly disintegratable oral tablet in the preparation of the tablet. In the preparation of a rapidly disintegratable oral tablet, the following two materials (a) and (b) are used to reduce the bitterness of a substance having a bitter taste contained in the tablet: (a) a granule which comprises the substance and an excipient and in which the bitterness of the substance is not reduced yet; and (b) a granule which comprises a water-soluble saccharide.
(FR)La présente invention concerne un procédé permettant de réduire l'amertume d'une substance amère contenue dans un comprimé oral à désintégration rapide dans la préparation dudit comprimé. Dans la préparation d'un comprimé oral à désintégration rapide, les deux matériaux (a) et (b) suivants sont utilisés pour réduire l'amertume d'une substance présentant un goût amer contenue dans le comprimé : (a) un granule comprenant la substance et un excipient, et dans lequel l'amertume de la substance n'est pas encore réduite; et (b) un granule comprenant un saccharide hydrosoluble.
(JA) 口腔内速崩壊性錠を製造するに際し、薬物の苦味を抑制する方法を提供する。  口腔内速崩壊性錠を製造するに際し、(a)苦味を有する薬物及び賦形剤を含有し、かつ、苦味の抑制されていない顆粒、並びに、(b)水溶性糖類を含有する顆粒を用いることにより、薬物の苦味を抑制する。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)