Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2007010459) PROTEIN EXTRACTED FROM PLANTS OF THE GENUS LUPINUS OR PRODUCED IN RECOMBINANT FORM, NUCLEOTIDE SEQUENCE ENCODING IT AND ITS USE IN ANIMAL NUTRITION, AS A PLANT GROWTH PROMOTER AND IN THE FIGHT AGAINST PATHOGENIC FUNGI
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/010459 International Application No.: PCT/IB2006/052403
Publication Date: 25.01.2007 International Filing Date: 13.07.2006
IPC:
C12N 15/82 (2006.01) ,C12N 15/29 (2006.01) ,C07K 14/415 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
82
for plant cells
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
29
Genes encoding plant proteins, e.g. thaumatin
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
415
from plants
Applicants:
INSTITUTO SUPERIOR DE AGRONOMIA [PT/PT]; Tapada Da Ajuda P-1349-017 Lisboa, PT (AllExceptUS)
DE SEIXAS BOAVIDA FERREIRA, Ricardo Manuel [PT/PT]; PT
VALADAS DA SILVA MONTEIRO, Sara Alexandra [PT/PT]; PT
NASCIMENTO TEIXEIRA, Artur Ricardo [PT/PT]; PT
BORGES LOUREIRO, Virgílio [PT/PT]; PT
Inventors:
DE SEIXAS BOAVIDA FERREIRA, Ricardo Manuel; PT
VALADAS DA SILVA MONTEIRO, Sara Alexandra; PT
NASCIMENTO TEIXEIRA, Artur Ricardo; PT
BORGES LOUREIRO, Virgílio; PT
Agent:
VIEIRA PEREIRA FERREIRA, Maria Silvina; CLARKE MODET & CO. Rua Castilho 50-5º P-1269-163 Lisboa, PT
Priority Data:
10332221.07.2005PT
10351128.06.2006PT
Title (EN) PROTEIN EXTRACTED FROM PLANTS OF THE GENUS LUPINUS OR PRODUCED IN RECOMBINANT FORM, NUCLEOTIDE SEQUENCE ENCODING IT AND ITS USE IN ANIMAL NUTRITION, AS A PLANT GROWTH PROMOTER AND IN THE FIGHT AGAINST PATHOGENIC FUNGI
(FR) PROTEINE EXTRAITE DE PLANTES DU GENRE LUPINIS OU PRODUITES SOUS FORMES RECOMBINEES, SEQUENCE NUCLEOTIDIQUE CODANT CETTE PROTEINE ET UTILISATION DE LA PROTEINE EN NUTRITION ANIMALE, COMME FACTEUR DE CROISSANCE DES PLANTES ET POUR LUTTER CONTRE LES CHAMPIGNONS PATHOGENES
Abstract:
(EN) This invention is related to the extraction of a protein from the seeds, cotyledons or plantlets of Lupinus genus, as well as to the way of producing it in recombinant form and of expressing it in genetically modified plants. Due to the exceptional characteristics exhibited by this protein in what concerns: its potent antifungal and anti-Oomycete activity, which confers great potential to the protein as a fungicide, (2) its strong plant growth promoter activity, particularly notorious on unhealthy or naturally weakened plants, (3) its extreme resistance to denaturation, which allows the use of the protein under field conditions, (4) its great susceptibility to proteolytic attack, which makes it harmless to the environment and nontoxic for man, and (5) its well balanced amino acid composition. It is claimed its use, or of any modification of the protein that maintains its biological properties, as a supplement in human or animal nutrition and as a fungicide, insecticide, growth promoter, fertilizer or in the preparation of genetically modified organisms.
(FR) L'invention concerne l'extraction d'une protéine à partir de graines, de cotylédons ou de plantules du genre Lupinis, ainsi qu'un procédé de production de cette protéine sous forme recombinée et de son expression dans des plantes génétiquement modifiées. En raison des caractéristiques exceptionnelles de cette protéine: (1) activité antifongique et anti-oomycète puissante, ce qui confère à la protéine un pouvoir fongicide important; (2) activité puissante comme facteur de croissance des plantes, en particulier sur des plantes connues, malades ou naturellement fragilisées; (3) extrême résistance à la dénaturation, ce qui permet d'utiliser la protéine dans des conditions naturelles; (4) grande sensibilité aux attaques protéolytiques, ce qui la rend inoffensive pour l'environnement et non toxique pour l'homme; et enfin, (5) composition en aminoacides bien équilibrée; l'invention revendique l'utilisation de cette protéine, ou toute modification qui préserve ses propriétés biologiques, comme complément alimentaire humain ou animal ainsi que comme fongicide, insecticide, facteur de croissance, fertilisant ou dans la préparation d'organismes génétiquement modifiés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
MXMX/a/2008/000979IL188907EP2221383EP1907550BRPI0613746-6BRPI0613746
EP2333086ZA2008/00581JP2009505637US20080300137ES2396722CN101365793
CA2617052EA200800091NZ565242AU2006271282DK1907550IN1194/DELNP/2008