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1. (WO2007010428) LUMINESCENCE SENSOR USING MULTI-LAYER SUBSTRATE STRUCTURE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/010428 International Application No.: PCT/IB2006/052300
Publication Date: 25.01.2007 International Filing Date: 07.07.2006
IPC:
G01J 1/58 (2006.01) ,G01N 21/76 (2006.01) ,G01N 33/58 (2006.01)
G PHYSICS
01
MEASURING; TESTING
J
MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
1
Photometry, e.g. photographic exposure meter
58
using luminescence generated by light
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
75
Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
76
Chemiluminescence; Bioluminescence
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58
involving labelled substances
Applicants:
KONINKLIJKE PHILIPS ELECTRONICS N.V. [NL/NL]; Groenewoudseweg 1 NL-5621 BA Eindhoven, NL (AllExceptUS)
VAN HERPEN, Maarten, M., J., W. [NL/NL]; NL (UsOnly)
KLUNDER, Derk, J., W. [NL/NL]; NL (UsOnly)
Inventors:
VAN HERPEN, Maarten, M., J., W.; NL
KLUNDER, Derk, J., W.; NL
Agent:
VAN WERMESKERKEN, Stephanie, C.; Prof. Holstlaan 6 NL-5656 AA Eindhoven, NL
Priority Data:
05106551.418.07.2005EP
Title (EN) LUMINESCENCE SENSOR USING MULTI-LAYER SUBSTRATE STRUCTURE
(FR) CAPTEUR DE LUMINESCENCE FAISANT APPEL A UNE STRUCTURE DE SUBSTRAT MULTICOUCHE
Abstract:
(EN) The present invention provides a luminescence sensor (2), such as e.g. a luminescence biosensor, comprising a multi-layer structure. The multi-layer structure comprises at least a first layer (2a) formed of a first material and a second layer (2b) formed of a second material. The first material has a first binding capacity towards luminophores and the second material has a second binding capacity towards luminophores, the first the first binding capacity being different from the second binding capacity. The luminescence sensor (2) according to the present invention shows a high sensitivity because it provides preferred binding sites for luminophores at locations where the combined excitation and detection efficiency is the highest.
(FR) L'invention concerne un capteur de luminescence (2), tel qu'un biocapteur de luminescence, qui comprend une structure multicouche. La structure multicouche comprend au moins une première couche (2a) formée d'un premier matériau et une seconde couche (2b) formée d'un second matériau. Le premier matériau possède une première capacité de liaison envers les luminophores et le second matériau possède une seconde capacité de liaison envers les luminophores, la première capacité de liaison étant différente de la seconde capacité de liaison. Le capteur de luminescence (2) de l'invention possède une sensibilité élevée étant donné qu'il offre aux luminophores des sites de liaison préférés en des emplacements où l'efficacité d'excitation et de détection combinée est la plus élevée.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1907805JP2009543023US20080197292CN101223425IN301/CHENP/2008