WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2007010342) IMPLANTABLE MEDICAL DEVICES COMPRISING A FLAVONOID OR DERIVATIVE THEREOF FOR PREVENTION OF RESTENOSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/010342    International Application No.:    PCT/IB2006/001848
Publication Date: 25.01.2007 International Filing Date: 26.06.2006
IPC:
A61L 31/16 (2006.01)
Applicants: SAHAJANAND BIOTECH PRIVATE LIMITED [IN/IN]; Sahajanand House, Parsi Street, Saiyedpura, Surat 395 003, Gujarat (IN) (For All Designated States Except US).
MANAGOLI, Nandkishore [IN/IN]; (IN) (For US Only)
Inventors: MANAGOLI, Nandkishore; (IN)
Agent: RAMAKRISHNAN, Omana; K & S Partners, 84-C, C-6 Lane, Off Central Avenue, Sainik Farms, New Delhi 110 062 (IN)
Priority Data:
05106528.2 15.07.2005 EP
60/699,509 15.07.2005 US
Title (EN) IMPLANTABLE MEDICAL DEVICES COMPRISING A FLAVONOID OR DERIVATIVE THEREOF FOR PREVENTION OF RESTENOSIS
(FR) DISPOSITIFS MEDICAUX IMPLANTABLES COMPRENANT UN FLAVONOIDE OU UN DERIVE DE CELUI-CI POUR LA PREVENTION DE LA RESTENOSE
Abstract: front page image
(EN)The present invention relates to implantable medical devices, such as stents, that comprise a composition for controlled delivery of flavonoids or a derivative thereof. The flavonoids are aimed at preventing or reducing secondary complications which can occur following implantation of the device such as e.g. occlusive and catastrophic vascular phenomena. The invention further relates to the inclusion of additional therapeutic agents in the system that may have antiproliferative, antimitotic, antimicrobial, anticoagulant, fibrinolytic, anti-inflammatory, immunosurpressive, and anti-angiogenic activities. The composition comprising the flavonoids and optional further therapeutic agents may be used in methods for treating or preventing narrowing or obstruction of a body passageway. In particular the devices and compositions of the invention are useful in methods for treating or preventing restenosis, e.g. subsequent to angioplasty and/or for preventing or reducing acute, subacute and chronic secondary complications associated with angioplasty, such as e.g. thrombus.
(FR)L'invention concerne des dispositifs médicaux implantables, par exemple des endoprothèses, qui comprennent une composition destinée à l'administration régulée de flavonoïdes ou un dérivé de ceux-ci. Les flavonoïdes permettent de prévenir ou de réduire les complications secondaires susceptibles de survenir à la suite de l'implantation du dispositif, par exemple des phénomènes vasculaires catastrophiques occlusifs. L'invention concerne en outre l'inclusion d'agents thérapeutiques additionnels dans le système susceptibles d'avoir des activités antiprolifératives, antimitotiques, antimicrobiennes, anticoagulantes, fibrinolytiques, anti-inflammatoires, immunosuppressives, et anti-angiogéniques. La composition comprenant les flavonoïdes et d'autres agents thérapeutiques optionnels peut servir dans des procédés de traitement ou de prévention du rétrécissement ou de l'obstruction d'un passage corporel. Plus précisément, les dispositifs et les compositions selon l'invention sont utilisés dans des procédés de traitement ou de prévention de la resténose, par exemple à la suite d'une angioplastie, et/ou de prévention ou de réduction de complications secondaires aiguës, subaiguës et chroniques associées à l'angioplastie, par exemple le thrombus.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)