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1. (WO2007010281) USE OF THIAZOLE DERIVATIVES AND ANALOGUES IN DISORDERS CAUSED BY FREE FATTY ACIDS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/010281 International Application No.: PCT/GB2006/002743
Publication Date: 25.01.2007 International Filing Date: 21.07.2006
IPC:
A61K 31/426 (2006.01) ,A61K 31/421 (2006.01) ,A61P 3/10 (2006.01) ,A61P 13/12 (2006.01) ,A61P 25/28 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
425
Thiazoles
426
1,3-Thiazoles
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
42
Oxazoles
421
1,3-Oxazoles, e.g. pemoline, trimethadione
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
08
for glucose homeostasis
10
for hyperglycaemia, e.g. antidiabetics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13
Drugs for disorders of the urinary system
12
of the kidneys
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
28
for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applicants:
BETAGENON AB [SE/SE]; Box 2339 S-103 18 Stockholm, SE (AllExceptUS)
ERIKSSON, Björn [SE/SE]; SE (UsOnly)
KURZ, Guido [DE/SE]; SE (UsOnly)
HEDBERG, Christian [SE/DE]; DE (UsOnly)
WESTMAN, Jacob [SE/SE]; SE (UsOnly)
Inventors:
ERIKSSON, Björn; SE
KURZ, Guido; SE
HEDBERG, Christian; DE
WESTMAN, Jacob; SE
Agent:
MCNEENEY, Stephen; Potter Clarkson LLP Park View House 58 The Ropewalk Nottingham NG1 5DD, GB
Priority Data:
0501721-521.07.2005SE
60/595,62021.07.2005US
60/744,42207.04.2006US
Title (EN) USE OF THIAZOLE DERIVATIVES AND ANALOGUES IN DISORDERS CAUSED BY FREE FATTY ACIDS
(FR) UTILISATION DE DERIVES ET D'ANALOGUES DE THIAZOLE DANS LES TROUBLES CAUSES PAR LES ACIDES GRAS LIBRES
Abstract:
(EN) There is provided a use of a compound of formula (I): wherein X, T, Y5 W, A1, A2, R1, R5 and R6 have meanings given in the description, for the manufacture of a medicament for the treatment of a disorder or condition caused by, linked to, or contributed to by, free fatty acids, such as hyperinsulinemia and associated conditions, including type 2 diabetes and the like.
(FR) L'invention concerne l'utilisation d'un composé représenté par la formule (I) dans laquelle X, T, Y5 W, A1, A2, R1, R5 et R6 sont tels que décrits dans la description, dans la fabrication d'un médicament utilisé dans le traitement d'un trouble ou d'un état pathologique causé par, ou associé à, ou provoqué par les acides gras libres, tels que l'hyperinsulinémie et les états pathologiques associés, y compris le diabète de type 2 et d'autres maladies semblables.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NO20076420NZ564511MXMX/a/2008/000973KR1020080032096IL188163EP1906956
BRPI0613624-9ZA2008/00399JP2009501776US20090136472CN101237866CA2614327
EA200800303AU2006271383IN559/DELNP/2008