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1. (WO2007010243) OLIGONUCLEOTIDE LIBRARY ENCODING RANDOMISED PEPTIDES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/010243 International Application No.: PCT/GB2006/002672
Publication Date: 25.01.2007 International Filing Date: 18.07.2006
IPC:
C12N 15/66 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
66
General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
Applicants:
ASTON UNIVERSITY [GB/GB]; Aston Triangle Birmingham B4 7ET, GB (AllExceptUS)
ASHRAF, Mohammed [GB/GB]; GB (UsOnly)
HUGHES, Marcus, Daniel [GB/GB]; GB (UsOnly)
HINE, Anna, Victoria [GB/GB]; GB (UsOnly)
Inventors:
ASHRAF, Mohammed; GB
HUGHES, Marcus, Daniel; GB
HINE, Anna, Victoria; GB
Agent:
ELSY, David ; Withers & Rogers LLP Goldings House 2 Hays Lane London SE1 2HW, GB
Priority Data:
0515131.122.07.2005GB
Title (EN) OLIGONUCLEOTIDE LIBRARY ENCODING RANDOMISED PEPTIDES
(FR) BIBLIOTHEQUE D'OLIGONUCLEOTIDES CODANT POUR DES PEPTIDES ALEATOIRES
Abstract:
(EN) The invention relates to a method of producing an oligonucleotide library comprising a plurality of oligonucleotides, each oligonucleotide in the library having at least one predetermined position, a randomisation codon selected from a defined group of codons, the codons within said defined group coding for different amino acids. Vector, host cells containing such libraries and kits for the production of such libraries are also provided.
(FR) L'invention se rapporte à un procédé de production d'une bibliothèque d'oligonucléotides comprenant une pluralité d'oligonucléotides présentant chacun au moins une position prédéterminée, un codon de randomisation sélectionné parmi un groupe défini de codons, les codons présents dans ledit groupe défini codant pour différents acides aminés. L'invention se rapporte également à un vecteur, à des cellules hôtes contenant de telles bibliothèques et à des trousses pour la production de ces bibliothèques.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2236612EP1907548US20090264313ES2378561ES2391159US20130130938
CA2616252PT2236612PT1907548DK1907548