WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2007009963) SUBSTITUTED AMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/009963    International Application No.:    PCT/EP2006/064302
Publication Date: 25.01.2007 International Filing Date: 17.07.2006
IPC:
C07D 409/14 (2006.01), C07D 513/04 (2006.01), A61K 31/55 (2006.01), A61P 7/02 (2006.01)
Applicants: BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE/DE]; Binger Str. 173, 55216 Ingelheim Am Rhein (DE) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG [DE/DE]; Binger Str. 173, 55216 Ingelheim Am Rhein (DE) (DE only).
GERLACH, Kai [DE/DE]; (DE) (For US Only).
PRIEPKE, Henning [DE/DE]; (DE) (For US Only).
PFAU, Roland [DE/DE]; (DE) (For US Only).
WIENEN, Wolfgang [DE/DE]; (DE) (For US Only).
SCHULER-METZ, Annette [DE/DE]; (DE) (For US Only).
DAHMANN, Georg [DE/DE]; (DE) (For US Only)
Inventors: GERLACH, Kai; (DE).
PRIEPKE, Henning; (DE).
PFAU, Roland; (DE).
WIENEN, Wolfgang; (DE).
SCHULER-METZ, Annette; (DE).
DAHMANN, Georg; (DE)
Agent: HAMMANN, Heinz; Binger Str. 173, 55216 Ingelheim Am Rhein (DE)
Priority Data:
05015588.6 19.07.2005 EP
Title (DE) SUBSTITUIERTE AMIDE, DEREN HERSTELLUNG UND DEREN VERWENDUNG ALS ARZNEIMITTEL
(EN) SUBSTITUTED AMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS
(FR) AMIDES SUBSTITUES, LEUR PREPARATION ET LEUR UTILISATION EN TANT QUE MEDICAMENT
Abstract: front page image
(DE)Gegenstand der vorliegenden Erfindung sind neue substituierte Amide der allgemeinen Formel (I), in denen D, L, M, W und B wie in der Beschreibung definiert sind, deren Tautomere, deren Enantiomere, deren Diastereomere, deren Gemische und deren Salze, insbesondere deren physiologisch verträgliche Salze mit anorganischen oder organischen Säuren oder Basen, welche wertvolle Eigenschaften aufweisen. Die Verbindungen wirken als Inhibitoren des Faktor Xa.
(EN)The present invention provides new substituted amides of the general formula (I) in which D, L, M, W and B are as defined in the description, their tautomers, their enantiomers, their diastereomers, mixtures thereof and salts thereof, particularly their physiologically acceptable salts with organic or inorganic acids or bases, which have valuable properties. The compounds act as inhibitors of factor Xa.
(FR)Nouveaux amides substitués de formule générale (I) dans laquelle D, L, M, W et B sont tels que définis dans la description, leurs tautomères, leurs énantiomères, leurs diastéréomères, leurs mélanges et leurs sels, en particulier leurs sels acceptables sur le plan physiologique avec des acides ou des bases inorganiques ou organiques, qui possèdent des propriétés précieuses. Ces composés ont une action d'inhibition du facteur Xa.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)