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1. (WO2007009793) SALT OF FUMARIC ACID AND 3-(2-DIMETHYLAMINO)METHYL(CYCLOHEX-1-YL))PHENOL AND ITS CRYSTALLINE FORMS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/009793    International Application No.:    PCT/EP2006/007161
Publication Date: 25.01.2007 International Filing Date: 20.07.2006
IPC:
C07C 215/64 (2006.01), A61K 31/135 (2006.01)
Applicants: GRÜNENTHAL GMBH [DE/DE]; Zieglerstrasse 6, 52078 Aachen (DE) (For All Designated States Except US).
GRUSS, Michael [DE/DE]; (DE) (For US Only).
HELL, Wolfgang [DE/DE]; (DE) (For US Only).
SZELAGIEWICZ, Martin [CH/CH]; (CH) (For US Only).
BERGHAUSEN, Jörg [DE/DE]; (DE) (For US Only).
DE PAUL, Susan, Margaret [US/CH]; (CH) (For US Only).
VON RAUMER, Markus [CH/CH]; (CH) (For US Only)
Inventors: GRUSS, Michael; (DE).
HELL, Wolfgang; (DE).
SZELAGIEWICZ, Martin; (CH).
BERGHAUSEN, Jörg; (DE).
DE PAUL, Susan, Margaret; (CH).
VON RAUMER, Markus; (CH)
Priority Data:
10 2005 034 973.0 22.07.2005 DE
Title (DE) SALZ VON FUMARSÄURE UND 3- (2-DIMETHYLAMINO) METHYL- ( CYCLOHEX-1-YL) ) PHENOL UN DESSEN KRISTALLINE FORMEN
(EN) SALT OF FUMARIC ACID AND 3-(2-DIMETHYLAMINO)METHYL(CYCLOHEX-1-YL))PHENOL AND ITS CRYSTALLINE FORMS
(FR) SEL D'ACIDE FUMARIQUE ET 3-(2-DIMETHYLAMINO)METHYLE-(CYCLOHEX-1-YLE) ) PHENOL ET SES FORMES CRISTALLINES
Abstract: front page image
(DE)3-[2-(Dimethylamino)methyl-(cyclohex-1-yl)]-phenol-Fumarat ist ein Analgetikum mit sehr guter Wirkung. Die kristalline Form B hat sich als chemisch sowie physikalisch sehr stabil erwiesen und eignet sich besonders für die Herstellung des Wirkstoffs und von pharmazeutischen Zusammensetzungen.
(EN)3-[2-(Dimethylamino)methyl(cyclohex-1-yl)]phenol fumarate is an analgesic with a very good action. The crystalline form B has proven to be very stable both chemically and physically and is particularly suitable for the production of the active principle and of pharmaceutical compositions.
(FR)L'invention concerne un 3-[2-(diméthylamino)méthyle-(cyclohex-1-yle)]-phénol-fumarate, un analgésique très efficace. La forme cristalline B a prouvé avoir une grande stabilité chimique et physique et elle est particulièrement adaptée à la production de la substance active et de compositions pharmaceutiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)