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1. (WO2007009788) A PROCESS AND COMPOSITION FOR MAKING OLANZAPINE FORM (I)
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/009788 International Application No.: PCT/EP2006/007138
Publication Date: 25.01.2007 International Filing Date: 20.07.2006
IPC:
C07D 495/04 (2006.01) ,A61K 31/55 (2006.01) ,A61P 25/18 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
495
Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
55
having seven-membered rings, e.g. azelastine, pentylenetetrazole
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
18
Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Applicants:
SYNTHON B.V. [NL/NL]; Microweg 22 NL-6545 CM Nijmegen, NL (AllExceptUS)
KELTJENS, Rolf [NL/NL]; NL (UsOnly)
THIJS, Lambertus [NL/NL]; NL (UsOnly)
Inventors:
KELTJENS, Rolf; NL
THIJS, Lambertus; NL
Agent:
PRINS, Hendrik, Willem ; Arnold & Siedsma Sweelinckplein 1 NL-2517 GK The Hague, NL
Priority Data:
60/700,71720.07.2005US
Title (EN) A PROCESS AND COMPOSITION FOR MAKING OLANZAPINE FORM (I)
(FR) PROCEDE ET COMPOSITION DESTINES A LA FABRICATION DE LA FORME 1 DE L'OLANZAPINE
Abstract:
(EN) The invention relates to a process for making crystalline olanzapine Form (I), which comprises reducing the pressure of a gas/supercritical fluid composition comprising carbon dioxide and olanzapine to precipitate crystalline olanzapine form (I) from said composition.
(FR) L'invention concerne un procédé destiné à la fabrication de la forme 1 cristalline de l'olanzapine, consistant à réduire la pression d'une composition supercritique/gazeuse renfermant du dioxyde de carbone et de l'olanzapine pour obtenir la précipitation de la forme 1 cristalline de l'olanzapine à partir de ladite composition.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)