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1. (WO2007009687) CARBONYL SUBSTITUTED PYRAZOLINE COMPOUNDS, THEIR PREPARATION AND USE AS CB1 RECEPTOR MODULATORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/009687 International Application No.: PCT/EP2006/006961
Publication Date: 25.01.2007 International Filing Date: 15.07.2006
IPC:
C07D 231/06 (2006.01) ,C07D 403/12 (2006.01) ,C07D 401/06 (2006.01) ,C07D 403/06 (2006.01) ,C07D 495/04 (2006.01) ,A61K 31/4155 (2006.01) ,A61P 3/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
231
Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
02
not condensed with other rings
06
having one double bond between ring members or between a ring member and a non-ring member
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
403
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
403
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
495
Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
415
1,2-Diazoles
4155
not condensed and containing further heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
04
Anorexiants; Antiobesity agents
Applicants:
LABORATORIOS DEL DR. ESTEVE, S.A. [ES/ES]; Avenida Mare de Deu de Montserrat, 221 E-08041 Barcelona, ES (AllExceptUS)
BUSCHMANN, Helmut, H. [DE/ES]; ES (UsOnly)
TORRENS JOVER, Antonio [ES/ES]; ES (UsOnly)
MAS PRIO, Jose [ES/ES]; ES (UsOnly)
QUINTANA RUIZ, Jordi Ramon [ES/ES]; ES (UsOnly)
DORDAL ZUERAS, Alberto [ES/ES]; ES (UsOnly)
Inventors:
BUSCHMANN, Helmut, H.; ES
TORRENS JOVER, Antonio; ES
MAS PRIO, Jose; ES
QUINTANA RUIZ, Jordi Ramon; ES
DORDAL ZUERAS, Alberto; ES
Agent:
PETERS, Hajo; Bosch Graf Von Stosch Jehle Patentanwaltsgesellschaft MBH Flüggenstrasse 13 80639 München, DE
Priority Data:
05384018.715.07.2005EP
06008579.226.04.2006EP
06008580.026.04.2006EP
06008581.826.04.2006EP
06008612.126.04.2006EP
60/705,43305.08.2005US
Title (EN) CARBONYL SUBSTITUTED PYRAZOLINE COMPOUNDS, THEIR PREPARATION AND USE AS CB1 RECEPTOR MODULATORS
(FR) COMPOSES DE PYRAZOLINE A SUBSTITUTION CARBONYLE, PREPARATION DE CEUX-CI ET UTILISATION DE CEUX-CI COMME MODULATEURS DES RECEPTEURS CB1
Abstract:
(EN) The present invention relates to substituted pyrazoline compounds, methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animals.
(FR) L'invention concerne des composés de pyrazoline substituée, des procédés de préparation de ceux-ci, des médicaments comprenant ces composés ainsi que l'utilisation de ceux-ci dans la préparation d'un médicament destiné au traitement d'êtres humains et d'animaux.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
DZDZP2008000430EP1910302