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1. (WO2007009607) NOVEL USE OF ACTIVATORS AND STIMULATORS OF SOLUBLE GUANYLATE CYCLASE FOR THE PREVENTION OR TREATMENT OF RENAL DISORDERS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/009607 International Application No.: PCT/EP2006/006601
Publication Date: 25.01.2007 International Filing Date: 06.07.2006
IPC:
A61K 31/437 (2006.01) ,A61K 31/4427 (2006.01) ,A61K 31/197 (2006.01) ,A61P 13/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
4353
ortho- or peri-condensed with heterocyclic ring systems
437
the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4427
containing further heterocyclic ring systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
195
having an amino group
197
the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid (GABA), beta-alanine, epsilon-aminocaproic acid, pantothenic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13
Drugs for disorders of the urinary system
12
of the kidneys
Applicants:
BAYER HEALTHCARE AG [DE/DE]; 51368 Leverkusen, DE (AllExceptUS)
KRAHN, Thomas [DE/DE]; DE (UsOnly)
STASCH, Johannes-Peter [DE/DE]; DE (UsOnly)
WEIMANN, Gerrit [DE/DE]; DE (UsOnly)
THIELEMANN, Wolfgang [DE/DE]; DE (UsOnly)
RINKE, Matthias [DE/DE]; DE (UsOnly)
Inventors:
KRAHN, Thomas; DE
STASCH, Johannes-Peter; DE
WEIMANN, Gerrit; DE
THIELEMANN, Wolfgang; DE
RINKE, Matthias; DE
Common
Representative:
BAYER HEALTHCARE AG; Law and Patents, Patents and Licensing 51368 Leverkusen, DE
Priority Data:
05015522.518.07.2005EP
Title (EN) NOVEL USE OF ACTIVATORS AND STIMULATORS OF SOLUBLE GUANYLATE CYCLASE FOR THE PREVENTION OR TREATMENT OF RENAL DISORDERS
(FR) NOUVELLE UTILISATION D'ACTIVATEURS ET DE STIMULATEURS DE LA GUANYLATE CYCLASE SOLUBLE PERMETTANT DE PREVENIR OU DE TRAITER DES TROUBLES RENAUX
Abstract:
(EN) The present invention relates generally to a use for the production of a medicament for the treatment of renal failure or renal hypertension and, more particularly, to a production of a medicament for improving the recovery from acute renal failure or renal hypertension by treatment with activators of soluble guanylate cyclase or stimulators of guanylate cyclase.
(FR) L'invention concerne en général la production d'un médicament permettant de traiter une insuffisance rénale ou l'hypertension rénale et, plus particulièrement, la production d'un médicament permettant d'améliorer la récupération après une insuffisance rénale ou une hypertension rénale aiguë par traitement à l'aide d'activateurs ou de stimulateurs de la guanylate cyclase soluble.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
MXMX/a/2008/000779KR1020080030669IL188657EP1906957BRPI0614001ZA2008/00466
JP2009501739US20100016305CN101222923CA2615426AU2006272088IN557/DELNP/2008