Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2007009462) TREATMENT OF MIGRAINE AND HEADACHES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/009462 International Application No.: PCT/DK2006/000418
Publication Date: 25.01.2007 International Filing Date: 14.07.2006
IPC:
A61P 25/06 (2006.01) ,A61K 45/00 (2006.01) ,A61K 31/155 (2006.01) ,A61K 31/5375 (2006.01) ,A61K 31/445 (2006.01) ,A61K 31/54 (2006.01) ,A61K 31/55 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
06
Antimigraine agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
13
Amines, e.g. amantadine
155
Amidines (), e.g. guanidine (H2N-C(NH)-NH2), isourea (HNC(OH)NH2), isothiourea (HNC(SH)-NH2)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
535
having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
5375
1,4-Oxazines, e.g. morpholine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
445
Non-condensed piperidines, e.g. piperocaine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
54
having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
55
having seven-membered rings, e.g. azelastine, pentylenetetrazole
Applicants:
REGION HOVEDSTADEN V/GLOSTRUP HOSPITAL [DK/DK]; Nordre Ringvej 57 2600 Glostrup, DK (AllExceptUS)
OLESEN, Inger, Jansen [DK/DK]; DK (UsOnly)
OLESEN, Jes [DK/DK]; DK (UsOnly)
Inventors:
OLESEN, Inger, Jansen; DK
OLESEN, Jes; DK
Agent:
HØIBERG A/S; St. Kongensgade 59A DK-1264 Copenhagen K, DK
Priority Data:
PA 2005 0104915.07.2005DK
Title (EN) TREATMENT OF MIGRAINE AND HEADACHES
(FR) TRAITEMENT DE LA MIGRAINE ET DES CEPHALEES
Abstract:
(EN) Treatment of migraine and headaches can be performed by the use of potassium channel blockers. The potassium channel blockers block KATp channels and/or BK channels. Also disclosed are the potassium channel blockers in the manufacture of a medicament for the treatment of migraine or headache. In respect of the KATP channels the potassium channel blocker may blocks channels with SUR2B subunits e.g. channels with SUR2B and Kir6.1 subunits. In respect of BKGa channels, any of the &agr;- or &bgr;-subunits of the channels may be blocked by a potassium channel blocke in the treatment of migraine and headaches.
(FR) L'invention concerne des bloqueurs des canaux potassiques destinés à être utilisés dans le traitement de la migraine et des céphalées. Ces bloqueurs des canaux potassiques bloquent les canaux KATP et/ou BK. L'invention concerne l'utilisation de ces bloqueurs des canaux potassiques dans la fabrication d'un médicament destiné au traitement de la migraine et des céphalées. Par rapport aux canaux KATP, les bloqueurs des canaux potassiques peuvent bloquer les canaux avec des sous-unités SUR2B, comme par exemple des canaux avec les sous-unités SUR2B et Kir6.1. Par rapport aux canaux BKGa, n'importe laquelle des sous-unités $g(a) ou $g(b) des canaux peut être bloquée par un bloqueur des canaux potassiques dans le traitement de la migraine ou des céphalées.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)