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1. (WO2007009393) THE USE OF CHLOROGENIC ACID IN THE MANUFACTURE OF MEDICAMENTS FOR INCREASING THE EFFECT OF BONE MARROW CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/009393    International Application No.:    PCT/CN2006/001795
Publication Date: 25.01.2007 International Filing Date: 21.07.2006
IPC:
A61K 31/216 (2006.01), A61P 43/00 (2006.01)
Applicants: ZHANG, Jie [CN/CN]; (CN).
ZHANG, Shu [CN/CN]; (CN) (For US Only).
ZHANG, Liang [CN/CN]; (CN) (For US Only).
LI, Xinquan [CN/CN]; (CN) (For US Only).
XU, Xiaoping [CN/CN]; (CN) (For US Only).
YONG, Zhiquan [CN/CN]; (CN) (For US Only).
BAO, Xu [CN/CN]; (CN) (For US Only)
Inventors: ZHANG, Jie; (CN).
ZHANG, Shu; (CN).
ZHANG, Liang; (CN).
LI, Xinquan; (CN).
XU, Xiaoping; (CN).
YONG, Zhiquan; (CN).
BAO, Xu; (CN)
Agent: LECOME INTELLECTUAL PROPERTY AGENT LTD.; Rm. 306, 3/F, Quantum Silver Plaza No. 23 Zhichun Rd. Haidian District Beijing 100083 (CN)
Priority Data:
200510088024.8 22.07.2005 CN
Title (EN) THE USE OF CHLOROGENIC ACID IN THE MANUFACTURE OF MEDICAMENTS FOR INCREASING THE EFFECT OF BONE MARROW CELLS
(FR) UTILISATION D'ACIDE CHLOROGENE DANS LA FABRICATION DE MEDICAMENTS POUR L'ACCROISSEMENT DE L'EFFET DE CELLULES DE MOELLE OSSEUSE
(ZH) 绿原酸在制备具有增加骨髓细胞功效的药物中的用途
Abstract: front page image
(EN)The use of chlorogenic acid in the manufacture of medicaments for increasing the effect of bone marrow cells . The pharmaceutical composition comprising chloroginic acid as active component . Chlorogenic acid can treat anaemia caused by many reasons , which comprise , but not to limited , blood loss anemia , hemolytic anemia , anhematopoietic anemia which include megaloblastic anemia , aregenerative anemia , and hypersplenia , as well as leucopeina , granulocytopeni and agranulocytopenia caused by many reasons , the change of macronucleus system casued by many reasons , for example , idiopathic thrombocytopenic purpura ; myelofibrosis , bone marrow infection caused by many reasons .
(FR)La présente invention a trait à l'utilisation d'acide chlorogène dans la fabrication de médicaments pour l'accroissement de l'effet de cellules de moelle osseuse. L'invention a également trait à la composition pharmaceutique comportant l'acide chlorogène en tant que principe actif. L'acide chlorogène peut traiter l'anémie provoquée par plusieurs causes, comprenant, mais de manière non limitative, l'anémie par perte sanguine, l'anémie hémolytique, l'anémie anhématopoïétique qui comprend l'anémie mégaloblaste, l'anémie arégénérative, et l'hyperplasie, ainsi que la leucopénie, la granulocytopénie et l'agranulocytopénie provoquées par plusieurs causes, la modification du système de macronucléus provoquée par plusieurs causes, par exemple, le purpura thrombocytopénique idiopathique, la myélofibrose, l'infection de la moelle osseuse provoquée par plusieurs causes.
(ZH)本发明提供了绿原酸Chlorogenic acid 在制备增加骨髓细胞功效的药物中的用途。本发明还提供了含有绿原酸为活性成分的药物组合物。绿原酸可治疗各种原因引起的贫血,且不仅仅限于失血性贫血、溶血性贫血,造血不良性贫血包括巨细胞性贫血、再生障碍性贫血和脾功能亢进,对各种原因引起的白细胞减少状态、粒细胞减少症、粒细胞缺乏症有治疗作用,对各种原因引起的巨核系统改变如特发性血小板减少性紫癜等有治疗作用;对各种原因引起的骨髓纤维化,骨髓感染有一定治疗作用。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)