Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2007009166) MODULATION OF GRANULOSA CELL APOPTOSIS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/009166 International Application No.: PCT/AU2006/001002
Publication Date: 25.01.2007 International Filing Date: 18.07.2006
IPC:
A61K 38/18 (2006.01) ,A61K 38/22 (2006.01) ,A61K 8/00 (2006.01) ,A61P 15/08 (2006.01) ,C12N 5/075 (2010.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
18
Growth factors; Growth regulators
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15
Drugs for genital or sexual disorders; Contraceptives
08
for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
075
Oocytes; Oogonia
Applicants:
ADELAIDE RESEARCH & INNOVATION PTY LTD [AU/AU]; Level 7 115 Grenfell Street Adelaide, South Australia 5000, AU (AllExceptUS)
GILCHRIST, Robert, Bruce [AU/AU]; AU (UsOnly)
THOMPSON, Jeremy [AU/AU]; AU (UsOnly)
HUSSEIN, Tamer [JO/AU]; AU (UsOnly)
Inventors:
GILCHRIST, Robert, Bruce; AU
THOMPSON, Jeremy; AU
HUSSEIN, Tamer; AU
Agent:
PHILLIPS ORMONDE & FITZPATRICK; Levels 21 & 22 367 Collins Street Melbourne, Victoria 3000, AU
Priority Data:
200590378218.07.2005AU
Title (EN) MODULATION OF GRANULOSA CELL APOPTOSIS
(FR) MODULATION DE L'APOPTOSE DES CELLULES DE LA GRANULOSA
Abstract:
(EN) The present invention relates to a method of modulating apoptosis of a granulosa cell. The method includes one or more of the following steps: (i) modulating the concentration and/or activity of BMP-15 and/or BMP-6 that the granulosa cell is exposed to; (ii) modulating activity of a BMP-15 dependent signalling pathway in the granulosa cell; and (iii) modulating activity of a BMP-6 dependent signalling pathway in a granulosa cell.
(FR) L'invention concerne un procédé de modulation de l'apoptose d'une cellule de la granulosa. Le procédé comprend une ou plusieurs étapes suivantes consistant: (i) à moduler la concentration et/ou l'activité de BMP-15 et/ou BMP-6 auxquelles la cellule de la granulosa est exposée; (ii) à moduler l'activité d'une voie de signalisation dépendante de BMP-15 dans la cellule de la granulosa; et (iii) à moduler l'activité d'une voie de signalisation dépendante de BMP-6 dans une cellule de la granulosa.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
KR1020080043783EP2228070EP1909820JP2009501533US20080274963CN101272804
JP2013215207CA2615006US20140073052AU2006272440DK2228070IN621/DELNP/2008