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Machine translation
1. (WO2007008926) ISOQUINOLINE COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/008926    International Application No.:    PCT/US2006/026947
Publication Date: 18.01.2007 International Filing Date: 11.07.2006
IPC:
C07D 217/02 (2006.01), A61K 31/472 (2006.01), A61P 27/06 (2006.01)
Applicants: AERIE PHARMACEUTICALS, INC. [US/US]; 7020 KIT CREEK ROAD, SUITE 270, P.O.Box 12320, Research Triangle Park, NC 27709 (US) (For All Designated States Except US).
DELONG, Mitchell, A. [US/US]; (US) (For US Only).
SZNAIDMAN, Marcos, L. [US/US]; (US) (For US Only).
OAKLEY, Robert, H. [US/US]; (US) (For US Only).
ECKHARDT, Allen, E. [US/US]; (US) (For US Only).
HUDSON, Christine [US/US]; (US) (For US Only).
YINGLING, Jeffrey, D. [US/US]; (US) (For US Only).
PEEL, Michael [GB/US]; (US) (For US Only).
RICHARDSON, Thomas, E. [US/US]; (US) (For US Only).
MURRAY, Claire, Louise [US/US]; (US) (For US Only).
RAO, Byappanahally N., Narasinga [IN/US]; (US) (For US Only).
HEASLEY, Brian, H. [US/US]; (US) (For US Only).
PATEL, Paresma, R. [US/US]; (US) (For US Only)
Inventors: DELONG, Mitchell, A.; (US).
SZNAIDMAN, Marcos, L.; (US).
OAKLEY, Robert, H.; (US).
ECKHARDT, Allen, E.; (US).
HUDSON, Christine; (US).
YINGLING, Jeffrey, D.; (US).
PEEL, Michael; (US).
RICHARDSON, Thomas, E.; (US).
MURRAY, Claire, Louise; (US).
RAO, Byappanahally N., Narasinga; (US).
HEASLEY, Brian, H.; (US).
PATEL, Paresma, R.; (US)
Agent: HARTWIG, Gregory, J.; MICHAEL BEST & FRIEDRICH LLP, 100 EAST WISCONSIN AVENUE, Suite 3300, Milwaukee, WI 53202-4108 (US)
Priority Data:
60/698,165 11.07.2005 US
Title (EN) ISOQUINOLINE COMPOUNDS
(FR) COMPOSES ISOQUINOLINIQUES
Abstract: front page image
(EN)Isoquinoline compounds are provided that influence, inhibit or reduce the action of a G-protein receptor kinase . Pharmaceutical compositions including therapeutically effective amounts of the isoquinoline compounds and pharmaceutically acceptable carriers are also provided. Various methods using the compounds and/or compositions to affect disease states or conditions such as cancer, osteoporosis and glaucoma are also provided.
(FR)La présente invention concerne des composés isoquinoliniques qui influencent, bloquent ou réduire l'action d'une kinase récepteur couplée à une protéine G. L'invention concerne également des compositions pharmaceutiques incluant des quantités thérapeutiquement actives de composés isoquinoliniques, et des vecteurs admis en pharmacie. L'invention concerne enfin divers procédés d'utilisation des composés et/ou compositions de façon à affecter des états ou conditions pathologiques tels que le cancer, l'ostéoporose et le glaucome.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)