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1. (WO2007008918) VIRUS VACCINES COMPRISING ENVELOPE-BOUND IMMUNOMODULATORY PROTEINS AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/008918 International Application No.: PCT/US2006/026927
Publication Date: 18.01.2007 International Filing Date: 10.07.2006
IPC:
C12N 7/00 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7
Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
Applicants:
WAYNE STATE UNIVERSITY [US/US]; 5057 Woodward Suite 6306 Detroit, MI 48202, US (AllExceptUS)
SUNDICK, Roy [US/US]; US (UsOnly)
ROBERTS, P., Christopher [US/US]; US (UsOnly)
YANG, Yufang [CN/US]; US (UsOnly)
HERBERT, Andrew, Scott [US/US]; US (UsOnly)
Inventors:
SUNDICK, Roy; US
ROBERTS, P., Christopher; US
YANG, Yufang; US
HERBERT, Andrew, Scott; US
Agent:
LUDWIG, S., Peter ; Darby & Darby P.C. P.O. Box 770 Church Street Station New York, NY 10008-0770, US
Priority Data:
60/697,77708.07.2005US
Title (EN) VIRUS VACCINES COMPRISING ENVELOPE-BOUND IMMUNOMODULATORY PROTEINS AND METHODS OF USE THEREOF
(FR) VACCINS DE VIRUS COMPRENANT DES PROTEINES IMMUNOMODULATRICES RELIEES A UNE ENVELOPPE, ET METHODE D'UTILISATION ASSOCIEE
Abstract:
(EN) The present invention provides novel virus vaccines with augmented, e.g., enhanced and/or extended immunogenicity. The virus vaccines of the invention comprise an envelope-bound immunomodulatory protein, e.g., a cytokine, chemokine or costimulatory molecule. The immunomodulatory protein serves as an adjuvant to augment, e.g., enhance or extend the immunogenicity of the virus vaccine, thereby augmenting, e.g., enhancing or extending immune response to the virus when administered to a subject.
(FR) L'invention concerne de nouveaux vaccins de virus présentant une immunogénicité accrue, par exemple améliorée ou étendue. Les vaccins de virus de l'invention comprennent une protéine immunmodulatrice reliée à l'enveloppe, par exemple, une molécule de cytokine, de chimiokine ou costimulante. Cette protéine immunomodulatrice sert d'adjuvant pour accroître, par exemple améliorer ou étendre l'immunogénicité du vaccin de virus, ce qui, par conséquent, accroît, par exemple, augmente ou étend la réponse immunitaire au virus, lorsque ce vaccin est administré à un patient.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
US20090214590