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Machine translation
1. (WO2007008870) TRANSGENIC MICE CARRYING HP-2 GENE AND USES AS MODELS FOR VASCULAR DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/008870    International Application No.:    PCT/US2006/026842
Publication Date: 18.01.2007 International Filing Date: 12.07.2006
IPC:
A01K 67/027 (2006.01), G01N 33/00 (2006.01)
Applicants: RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES [IL/IL]; Efron Street, Bat Galim, P.O. Box 9697, Haifa 31096 (IL) (For All Designated States Except US).
LEVY, Andrew [US/IL]; (IL) (For US Only).
LEVY, Nina [--/IL]; (For US Only)
Inventors: LEVY, Andrew; (IL).
LEVY, Nina;
Agent: COHEN, Mark, S.; Pearl Cohen Zedek Latzer, LLP, 1500 Broadway, 12th Floor, New York, NY 10036 (US)
Priority Data:
60/698,012 12.07.2005 US
Title (EN) TRANSGENIC MICE CARRYING HP-2 GENE AND USES AS MODELS FOR VASCULAR DISEASES
(FR) SOURIS TRANSGENIQUE PORTANT LE GENE HP-2 ET UTILISATIONS COMME MODELE POUR DES MALADIES VASCULAIRES
Abstract: front page image
(EN)This invention provides transgenic mice carrying the humanized Hp-2 allele for haptoglobin. Specifically, provided herein is methods of the use of these transgenic mice in the diagnosis and rational drug design of compounds to be used in the treatment of vascular complications in diabetic subjects carrying the Hp-2 gene.
(FR)L'invention concerne une souris transgénique qui porte l'allèle humanisé Hp-2 de l'haptoglobine. Plus spécifiquement, l'invention concerne des procédés d'utilisation de cette souris transgénique dans le diagnostic et l'élaboration rationnelle de médicaments à partir de composés servant à traiter les complications vasculaires chez les sujets diabétiques portant le gène Hp-2.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)