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1. (WO2007008780) COMPOSITIONS AND METHODS FOR ELICITING AN IMMUNE RESPONSE TO ESCAPE MUTANTS OF TARGETED THERAPIES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/008780 International Application No.: PCT/US2006/026710
Publication Date: 18.01.2007 International Filing Date: 10.07.2006
IPC:
A61K 39/12 (2006.01) ,A61K 39/00 (2006.01) ,A61P 31/12 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12
Antivirals
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
GLOBEIMMUNE, INC. [US/US]; 1450 Infinite Drive Louisville, Colorado 80027, US (AllExceptUS)
APELIAN, David [US/US]; US (UsOnly)
FRANZUSOFF, Alex [US/US]; US (UsOnly)
RODELL, Timothy, C. [US/US]; US (UsOnly)
Inventors:
APELIAN, David; US
FRANZUSOFF, Alex; US
RODELL, Timothy, C.; US
Agent:
MONROY, Gladys, H. ; Morrison & Foerster LLP 755 Page Mill Road Palo Alto, CA 94304-1018, US
Priority Data:
60/698,38111.07.2005US
Title (EN) COMPOSITIONS AND METHODS FOR ELICITING AN IMMUNE RESPONSE TO ESCAPE MUTANTS OF TARGETED THERAPIES
(FR) COMPOSITIONS ET PROCEDES PERMETTANT D'ELICITER UNE REPONSE IMMUNE A DES MUTANTS D'ECHAPPEMENT DE THERAPIES CIBLEES
Abstract:
(EN) Provided herein are cells, vectors and viruses in association with a mutant polypeptide that has emerged in response to a therapeutic or prophylactic agent; compositions comprising such cells, vectors and viruses and methods for their use in eliciting an immune response to the mutant polypeptide. In some examples, the immune response is a cellular immune response.
(FR) L'invention concerne des cellules, des vecteurs et des virus conjointement avec un polypeptide mutant ayant émergé en réponse à un agent thérapeutique ou prophylactique; des compositions comprenant de tels cellules, vecteurs et virus et des procédés d'utilisation de ceux-ci permettant d'éliciter une réponse immune au polypeptide mutant. Dans quelques exemples, la réponse immune est une réponse cellulaire immune.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
MXMX/a/2008/000587KR1020080043775IL188717SG163572EP1906997BRPI0613025-9
JP2009500454EP2371381US20100034840CN101262883CA2614884AU2006268333
AU2012216725IN116/KOLNP/2008