Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2007008690) METHODS FOR MONITORING NEUROINFLAMMATORY DESTRUCTION OF NEURONS AND FOR TREATING DISEASES HAVING AN INFLAMMATORY COMPONENT RELATED TO PHOSPHOLIPASE A2
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/008690 International Application No.: PCT/US2006/026568
Publication Date: 18.01.2007 International Filing Date: 10.07.2006
IPC:
G01N 33/00 (2006.01) ,G01N 33/53 (2006.01) ,G01N 33/564 (2006.01) ,A61K 39/395 (2006.01) ,A61K 39/00 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
564
for pre-existing immune complex or autoimmune disease
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
Applicants:
PHILADELPHIA HEALTH & EDUCATION CORPORATION, D/B/A DREXEL UNIVERSITY COLLEGE OF MEDICINE [US/US]; 3225 Arch Street, Ground Floor Philadelphia, PA 19104, US (AllExceptUS)
CUNNINGHAM, Timothy, J. [US/US]; US (UsOnly)
YAO, Lihua [US/US]; US (UsOnly)
GREENSTEIN, Jeffrey, I. [US/US]; US (UsOnly)
Inventors:
CUNNINGHAM, Timothy, J.; US
YAO, Lihua; US
GREENSTEIN, Jeffrey, I.; US
Agent:
DOYLE, Kathryn; DRINKER BIDDLE & REATH LLP ONE LOGAN SQUARE 18th And Cherry Streets Philadelphia, PA 19103, US
Priority Data:
60/697,59808.07.2005US
Title (EN) METHODS FOR MONITORING NEUROINFLAMMATORY DESTRUCTION OF NEURONS AND FOR TREATING DISEASES HAVING AN INFLAMMATORY COMPONENT RELATED TO PHOSPHOLIPASE A2
(FR) METHODES PERMETTANT DE CONTROLER LA DESTRUCTION DES NEURONES PAR NEUROINFLAMMATION ET DE TRAITER DES MALADIES PRESENTANT UNE COMPOSANTE INFLAMMATOIRE LIEE A LA PHOSPHOLIPASE A2
Abstract:
(EN) The present invention relates to methods useful to monitor central and peripheral nervous system neuron/axon destruction resulting from an increase in acute phase inflammatory enzymes. The methods have applicability to monitoring the progress of neurological diseases, including multiple sclerosis and Alzheimer's disease, as well as neuroinflammatory damage that results from sports injuries, vigorous physical activity or any form of physical abuse. The invention further relates to methods of treating multiple sclerosis or other diseases with an inflammatory component related to phospolipase A2.
(FR) L'invention concerne des méthodes permettant de contrôler la destruction des neurones/axones dans le système nerveux central et périphérique, due à une augmentation des enzymes en phase aiguë inflammatoire. Les méthodes peuvent être utilisées pour surveiller l'évolution de maladies neurologiques, y compris la sclérose en plaques et la maladie d'Alzheimer, ainsi que pour surveiller des dommages neuroinflammatoires provoqués par des blessures du sport, un activité physique intense ou toute autre forme d'exercice physique excessif. L'invention concerne également des méthodes de traitement de la sclérose en plaques ou d'autres maladies présentant une composante inflammatoire liée à la phospholipase A2.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
IL188342EP1915613JP2009500040US20090181879CA2614737AU2006269327