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1. (WO2007008474) 3 -ESTER PRODRUGS OF ESTRADIOL
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/008474 International Application No.: PCT/US2006/025853
Publication Date: 18.01.2007 International Filing Date: 03.07.2006
IPC:
C07J 41/00 (2006.01) ,C07J 43/00 (2006.01) ,C07J 1/00 (2006.01) ,A61K 31/565 (2006.01) ,A61K 31/58 (2006.01) ,A61P 5/30 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
J
STEROIDS
41
Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
J
STEROIDS
43
Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta[a]hydrophenanthrene skeleton
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
J
STEROIDS
1
Normal steroids containing carbon, hydrogen, halogen, or oxygen, not substituted in position 17 beta by a carbon atom, e.g. oestrane, androstane
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
565
not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
58
containing heterocyclic rings, e.g. aldosterone, danazol, stanozolol, pancuronium, digitogenin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
5
Drugs for disorders of the endocrine system
24
of the sex hormones
30
Oestrogens
Applicants:
WARNER CHILCOTT COMPANY, INC. [US/US]; P.O. BOX 1005 Union Street Km 1.1 Fajardo, Puerto Rico 00738-1005, US (AllExceptUS)
KEOWN, James [GB/IE]; IE (UsOnly)
KING, John, Alexander [GB/IE]; IE (UsOnly)
McILROY, James, William [GB/IE]; IE (UsOnly)
GILLIGAN, Claire [GB/IE]; IE (UsOnly)
ARMSTRONG, William, Paul [GB/IE]; IE (UsOnly)
Inventors:
KEOWN, James; IE
KING, John, Alexander; IE
McILROY, James, William; IE
GILLIGAN, Claire; IE
ARMSTRONG, William, Paul; IE
Agent:
MANDRA, Raymond, R.; Fitzpatrick, Cella, Harper & Scinto 30 Rockefeller Plaza New York, NY 10112-3801, US
Priority Data:
60/698,86612.07.2005US
Title (EN) 3 -ESTER PRODRUGS OF ESTRADIOL
(FR) NOUVEAUX PROMEDICAMENTS D'ESTRADIOL
Abstract:
(EN) The present invention is a prodrug derivative of estradiol according to Formula I:
(FR) La présente invention concerne un dérivé de promédicament d'estradiol de formule I.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
MXMX/a/2008/000412IL187633EP1910402CN101228177CA2610481IN9593/DELNP/2007