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1. (WO2007008350) PHARMACEUTICAL FORMULATIONS OF ENDO-N-(9- METHYL-9-AZABICYCLO[3 .3.1]NON-3-YL)-1-METHYL-1H-INDAZOLE-3-CARBOXAMIDE HYDROCHLORIDE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/008350 International Application No.: PCT/US2006/023933
Publication Date: 18.01.2007 International Filing Date: 19.06.2006
IPC:
A61K 9/08 (2006.01) ,A61K 47/02 (2006.01) ,A61K 47/10 (2006.01) ,A61K 47/12 (2006.01) ,A61K 31/439 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
08
Solutions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
02
Inorganic compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
10
Alcohols; Phenols; Salts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
12
Carboxylic acids; Salts or anhydrides thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
439
the ring forming part of a bridged ring system, e.g. quinuclidine
Applicants:
BAXTER INTERNATIONAL INC. [US/US]; One Baxter Parkway Deerfield, IL 60015, US (AllExceptUS)
BAXTER HEALTHCARE S.A. [CH/CH]; Hertistrasse 2 Ch-8306 Wallisellen, CH (AllExceptUS)
SINGH, Kiran Pal [US/US]; US (UsOnly)
YUEN, Pui-Ho [US/US]; US (UsOnly)
Inventors:
SINGH, Kiran Pal; US
YUEN, Pui-Ho; US
Agent:
JACONETTY, Kenneth E. ; Baxter International Inc. One Baxter Parkway Deerfield, IL 60015, US
Priority Data:
11/326,95705.01.2006US
60/698,77613.07.2005US
Title (EN) PHARMACEUTICAL FORMULATIONS OF ENDO-N-(9- METHYL-9-AZABICYCLO[3 .3.1]NON-3-YL)-1-METHYL-1H-INDAZOLE-3-CARBOXAMIDE HYDROCHLORIDE
(FR) FORMULATIONS PHARMACEUTIQUES CHLORHYDRATE D'ENDO-N-(9- METHYL-9-AZABICYCLO[3 .3.1]NON-3-YL)-1-METHYL-1H-INDAZOLE-3-CARBOXAMIDE
Abstract:
(EN) A pharmaceutical formulation suitable for multi-dose administration comprising endo-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxanide hydrochloride, a preservative selected from the group consisting of alkyl paraben and phenol, and a buffer selected from the group consisting of acetate and phosphate buffers is disclosed.
(FR) L'invention concerne une formulation pharmaceutique appropriée pour une administration en doses multiples, qui comprend: un chlorhydrate d'endo-n-(9- méthyl-9-azabicyclo[3 .3.1]non-3-yl)-1-méthyl-1h-indazole-3-carboxamide; un conservateur sélectionné dans le groupe constitué par paraben et phénol d'alkyle; et un tampon sélectionné dans le groupe constitué par des tampons d'acétate et de phosphate.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
MXMX/a/2008/000669EP1909756JP2009501222CN101252910CA2615053NZ565054
AU2006269628