Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2007008200) WORTMANNIN ANALOGS AND METHODS OF USING SAME IN COMBINATION WITH CHEMOTHERAPEUTIC AGENTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/008200 International Application No.: PCT/US2005/024429
Publication Date: 18.01.2007 International Filing Date: 11.07.2005
IPC:
A61K 31/40 (2006.01) ,A61K 31/35 (2006.01) ,C07D 311/78 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
311
Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02
ortho- or peri-condensed with carbocyclic rings or ring systems
78
Ring systems having three or more relevant rings
Applicants:
PROLX PHARMACEUTICALS CORP. [US/US]; 221 East 6th Street Tucson, AZ 85705, US (AllExceptUS)
ARIZONA BOARD OF REGENTS, ACTING ON BEHALF OF THE UNIVERSITY OF ARIZONA [US/US]; 888 N. Euclid Avenue P.O. Box 201158 Tucson, AZ 85721-0158, US (AllExceptUS)
UNIVERSITY OF PITTSBURGH [US/US]; 200 Gardner Steel Conference Center Thackeray and O'Hara Streets Pittsburgh, PA 15213, US (AllExceptUS)
KIRKPATRICK, Lynn [US/US]; US (UsOnly)
POWIS, Garth [US/US]; US (UsOnly)
WIPF, Peter [CH/US]; US (UsOnly)
Inventors:
KIRKPATRICK, Lynn; US
POWIS, Garth; US
WIPF, Peter; US
Agent:
MILLER, Raymond, A.; Pepper Hamilton LLP One Mellon Center, 50th Floor 500 Grant Street Pittsburgh, 15219, US
Priority Data:
60/586,68709.07.2004US
Title (EN) WORTMANNIN ANALOGS AND METHODS OF USING SAME IN COMBINATION WITH CHEMOTHERAPEUTIC AGENTS
(FR) ANALOGUES DE WORTMANNIN ET METHODES D'UTILISATION DE CEUX-CI EN COMBINAISON AVEC DES AGENTS CHIMIOTHERAPEUTIQUES
Abstract:
(EN) wortmannin analogs and their use in inhibiting PI-3-kinase activity in mammals and the treatment of cancer and tumor formation in a subject are described herein, ehich may be administered with other chemotherapeutic agents in the treatment of cancer.
(FR) L'invention concerne des analogues de Wortmannin et leur utilisation dans l'inhibition de l'activité de la PI-3-kinase chez les mammifères, et le traitement du cancer et la formation de tumeurs chez un sujet. Lesdits analogues peuvent être utilisés avec d'autres agents chimiothérapeutiques dans le traitement du cancer.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
MXMX/a/2007/000319AU2005333515EP1901738EP2301533JP2009500408CA2578336
AU2005333515