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1. (WO2007008158) METHOD FOR DIAGNOSING MULTIPLE SCLEROSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/008158    International Application No.:    PCT/SE2006/000866
Publication Date: 18.01.2007 International Filing Date: 10.07.2006
IPC:
G01N 33/68 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje (SE) (For All Designated States Except US).
ERIKSSON, Bodil [SE/SE]; (SE) (For US Only).
FRANZÉN, Bo [SE/SE]; (SE) (For US Only).
OTTERVALD, Jan [SE/SE]; (SE) (For US Only)
Inventors: ERIKSSON, Bodil; (SE).
FRANZÉN, Bo; (SE).
OTTERVALD, Jan; (SE)
Agent: ASTRAZENECA; Global Intellectual Property, S-151 85 Södertälje (SE)
Priority Data:
0501643-1 11.07.2005 SE
Title (EN) METHOD FOR DIAGNOSING MULTIPLE SCLEROSIS
(FR) METHODE SERVANT A DIAGNOSTIQUER LA SCLEROSE EN PLAQUES
Abstract: front page image
(EN)The present invention relates to methods for diagnosing multiple sclerosis in a subject, the method, comprising determining the level of phosphorylation of a marker in a biological sample from the subject, wherein the marker is selected from α1-antitrypsin (a1AT) and vitamin D binding protein (VDBP); and comparing the level of phosphorylation of the marker in the sample to a reference value.
(FR)L'invention concerne des méthodes servant à diagnostiquer la sclérose en plaques chez un individu et consistant à déterminer le niveau de phosphorylation d'un marqueur dans un spécimen biologique prélevé chez cet individu, ce marqueur étant sélectionné parmi l'α1-antitrypsine (α1AT) et la protéine de liaison à la vitamine D (VDBP), puis à comparer le niveau de phosphorylation du marqueur dans le spécimen à une valeur de référence.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)