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1. (WO2007007943) PHARMACEUTICAL COMPOSITION FOR TREATING OF CANCER COMPRISING PYRIDYLPYRIDAZINE COMPOUNDS OR THEIR TRANSITION METAL COMPLEXES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/007943 International Application No.: PCT/KR2006/000449
Publication Date: 18.01.2007 International Filing Date: 07.02.2006
Chapter 2 Demand Filed: 15.12.2006
IPC:
A61K 31/501 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
50
Pyridazines; Hydrogenated pyridazines
501
not condensed and containing further heterocyclic rings
Applicants:
THE INDUSTRY AND ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) [KR/KR]; 220 Gung-dong, Yuseong-gu, Daejeon 305-754, KR (AllExceptUS)
SUNG, Nack-do [KR/KR]; KR (UsOnly)
Inventors:
SUNG, Nack-do; KR
Agent:
KIM, Won Joon; 205 Gold Venture Tower, 386, Mannyeon-dong Seo-gu Daejeon 302-834, KR
Priority Data:
10-2005-006371014.07.2005KR
Title (EN) PHARMACEUTICAL COMPOSITION FOR TREATING OF CANCER COMPRISING PYRIDYLPYRIDAZINE COMPOUNDS OR THEIR TRANSITION METAL COMPLEXES
(FR) COMPOSITION PHARMACEUTIQUE SERVANT À TRAITER UN CANCER COMPRENANT DES COMPOSÉS DE PYRIDYLPYRIDAZINE OU LEURS COMPLEXES DE MÉTAUX DE TRANSITION
Abstract:
(EN) The present invention relates to a pharmaceutical composition for the treatment of cancer, which contains, as an active ingredient, a pyridylpyridazine compound or a transition metal complex thereof. As described above, the pyridylpyridazine compounds according to the present invention and the transition metal complexes thereof have anticancer activity and can be easily prepared at low cost. Thus, these compounds are useful as anticancer agents against various cancers, including lung cancer, adenocarcinoma, skin cancer, colon cancer, uterine cancer and brain cancer, which are expressed due to immune system abnormality.
(FR) La présente invention concerne une composition pharmaceutique pour le traitement d'un cancer, laquelle contient, comme ingrédient actif, un composé de pyridylpyridazine ou un complexe de métal de transition de celui-ci. Comme décrit ci-dessus, les composés de pyridylpyridazine selon la présente invention et les complexes de métaux de transition de ceux-ci ont une activité anticancéreuse et peuvent être facilement préparés à faible coût. Ainsi, ces composés sont utiles comme agents anticancéreux contre différents cancers, dont le cancer du poumon, l'adénocarcinome, le cancer de la peau, le cancer du colon, le cancer de l'utérus et le cancer du cerveau, lesquels sont exprimés à cause d'une anomalie du système immunitaire.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: Korean (KO)
Also published as:
US20090036418