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1. (WO2007007686) COMPOSITION FOR PREVENTION OF OCCURRENCE OF CARDIOVASCULAR EVENT
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/007686 International Application No.: PCT/JP2006/313609
Publication Date: 18.01.2007 International Filing Date: 07.07.2006
IPC:
A61K 31/232 (2006.01) ,A61K 45/00 (2006.01) ,A61P 9/10 (2006.01) ,A61P 43/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
22
of acyclic acids, e.g. pravastatin
23
of acids having a carboxyl group bound to a chain of seven or more carbon atoms
232
having three or more double bonds, e.g. etretinate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
10
for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
Applicants:
持田製薬株式会社 MOCHIDA PHARMACEUTICAL CO., LTD. [JP/JP]; 〒1608515 東京都新宿区四谷一丁目7番地 Tokyo 7, Yotsuya 1-chome, Shinjuku-ku, Tokyo 1608515, JP (AllExceptUS)
Inventors:
横山 光宏 YOKOYAMA, Mitsuhiro; JP
折笠 秀樹 ORIGASA, Hideki; JP
松▲崎▼ 益▲徳▼ MATSUZAKI, Masunori; JP
松澤 佑次 MATSUZAWA, Yuji; JP
齋藤 康 SAITO, Yasushi; JP
石川 雄一 ISHIKAWA, Yuichi; JP
及川 眞一 OIKAWA, Shinichi; JP
佐々木 淳 SASAKI, Jun; JP
菱田 仁士 HISHIDA, Hitoshi; JP
板倉 弘重 ITAKURA, Hiroshige; JP
北 徹 KITA, Toru; JP
北畠 顯 KITABATAKE, Akira; JP
中谷 矩章 NAKAYA, Noriaki; JP
坂田 利家 SAKATA, Toshiie; JP
島田 和幸 SHIMADA, Kazuyuki; JP
白土 邦男 SHIRATO, Kunio; JP
Agent:
渡辺 望稔 WATANABE, Mochitoshi; 〒1010032 東京都千代田区岩本町2丁目12番5号 早川トナカイビル3階 Tokyo Hayakawa-tonakai Bldg. 3F 12-5, Iwamoto-cho 2-chome Chiyoda-ku Tokyo1010032, JP
Priority Data:
2005-20050308.07.2005JP
Title (EN) COMPOSITION FOR PREVENTION OF OCCURRENCE OF CARDIOVASCULAR EVENT
(FR) COMPOSITION POUR LA PRÉVENTION DE LA SURVENUE D'UN ÉVÉNEMENT CARDIOVASCULAIRE
(JA) 心血管イベント発症予防用組成物
Abstract:
(EN) A composition for prevention of the occurrence and/or recurrence of a cardiovascular event comprising ethyl eicosapentaenoate ester as an active ingredient, which is useful for the prevention of the occurrence and/or recurrence of a cardiovascular event, and is particularly expected to show a preventive effect on the occurrence and/or recurrence of a cardiovascular event that occurs and/or recurs in a hyperlipemia patient despite having received a therapy with HMG-CoA RI, more particularly a cardiovascular event that occurs after passing through an unstable period after the application of cardiovascular reconstruction.
(FR) L'invention concerne une composition pour la prévention de la survenue et/ou de la récurrence d'un événement cardiovasculaire comprenant un ester d'éicosapentaénoate d'éthyle comme principe actif, qui est utile dans la prévention de la survenue et/ou de la récurrence d'un événement cardiovasculaire, et dont on attend particulièrement qu'il ait un effet préventif sur ces événements qui surviennent et/ou sont récurrents chez un patient hyperlipémique en dépit de l'administration d'un traitement par HMG-CoA RI, plus particulièrement un événement cardiovasculaire qui survient à la suite d'une période instable faisant suite à une reconstruction cardiovasculaire.
(JA)  心血管イベント発症および/または再発の予防に有用で、特に、高脂血症患者でHMG-CoA RIによる治療を行なったにもかかわらず発症および/または再発する心血管イベント、あるいは特に心血管再建術施行後不安定期を経過した後に起こる心血管イベントの発症および/または再発の予防効果が期待され、イコサペント酸エチルエステルを有効成分として含有する、心血管イベント発症および/または再発予防用組成物の提供。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
NO20065384EP1790339BRPI0613704-0JP2007039452JP2008050367US20070021504
JP2012193211US20130065956CN101217952CN102526733CA2570763ES2489741
KR1020130137055US20160045469