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1. WO2007007149 - ANDROGEN MODULATORS

Publication Number WO/2007/007149
Publication Date 18.01.2007
International Application No. PCT/IB2006/001860
International Filing Date 03.07.2006
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
255
Carboxylic acid nitriles
49
having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
54
containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
275
Nitriles; Isonitriles
277
having a ring, e.g. verapamil
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
5
Drugs for disorders of the endocrine system
24
of the sex hormones
26
Androgens
C07C 255/54 (2006.01)
A61K 31/277 (2006.01)
A61P 5/26 (2006.01)
CPC
C07C 255/54
Applicants
  • WARNER-LAMBERT COMPANY LLC [US/US]; 201 Tabor Road Morris Plains, NJ 07950, US (AllExceptUS)
  • HU, Lain-Yen [US/US]; US (UsOnly)
  • LEFKER, Bruce, Allen [US/US]; US (UsOnly)
  • KOSTLAN, Catherine, Rose [US/US]; US (UsOnly)
  • BERTOLINO, Arthur, Peter [US/US]; US (UsOnly)
Inventors
  • HU, Lain-Yen; US
  • LEFKER, Bruce, Allen; US
  • KOSTLAN, Catherine, Rose; US
  • BERTOLINO, Arthur, Peter; US
Agents
  • FULLER, Grover, F., Jr.; Pfizer Inc. 150 East 42nd Street New York, NY 10017-5612, US
Priority Data
60/698,56512.07.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANDROGEN MODULATORS
(FR) MODULATEUR D'ANDROGENE
Abstract
(EN)
The present invention is directed to a new class of benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
(FR)
La présente invention concerne une nouvelle classe de benzonitriles et leur utilisation comme modulateurs de récepteur d'androgènes. D'autres aspects de l'invention concernent l'utilisation de ces composés pour réduire l'excès de sécrétion de sébum et pour stimuler la croissance des cheveux.
Latest bibliographic data on file with the International Bureau