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1. (WO2007007095) PHARMACEUTICAL COMPOSITIONS COMPRISING A TGF-BETA SUPERFAMILY MEMBER
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/007095 International Application No.: PCT/GB2006/002574
Publication Date: 18.01.2007 International Filing Date: 12.07.2006
IPC:
A61K 38/18 (2006.01) ,A61P 29/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
18
Growth factors; Growth regulators
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
Applicants:
RENOVO LTD [GB/GB]; Incubator Building 48 Grafton Street Manchester M13 9XX, GB (AllExceptUS)
FERGUSON, Mark [GB/GB]; GB (UsOnly)
O'KANE, Sharon [GB/GB]; GB (UsOnly)
LAVERTY, Hugh [GB/GB]; GB (UsOnly)
OCCLESTON, Nick [GB/GB]; GB (UsOnly)
KELLY, Jane [GB/GB]; GB (UsOnly)
BURRILL, Wayne [GB/GB]; GB (UsOnly)
Inventors:
FERGUSON, Mark; GB
O'KANE, Sharon; GB
LAVERTY, Hugh; GB
OCCLESTON, Nick; GB
KELLY, Jane; GB
BURRILL, Wayne; GB
Agent:
ARMSTRONG, Iain, Cheshire; Marks & Clerk Sussex House 83-85 Mosley Street Manchester M2 3LG, GB
Priority Data:
0514259.112.07.2005GB
0514260.912.07.2005GB
Title (EN) PHARMACEUTICAL COMPOSITIONS COMPRISING A TGF-BETA SUPERFAMILY MEMBER
(FR) COMPOSITIONS PHARMACEUTIQUES
Abstract:
(EN) The invention provides pharmaceutical compositions comprising TGF-β superfamily members and sugars, the compositions allowing improved recovery and/or increased biological activity of the TGF- β superfamily member incorporated therein. The invention also relates to uses of sugars to improve the recovery or increase the biological activity of TGF-β superfamily members in a pharmaceutical composition. Uses of the pharmaceutical compositions are also described, particularly with reference to wound healing and fibrosis. Furthermore, the invention discloses medicaments for the prevention or reduction of injection pain.
(FR) L'invention concerne des compositions pharmaceutiques renfermant des membres de la superfamille TGF-β ainsi que des sucres, les compositions permettant une récupération améliorée et/ou une activité biologique accrue de l'élément de la superfamille TGF-β qu'elles contiennent. L'invention concerne également les utilisations de sucres pour améliorer la récupération ou l'augmentation de l'activité biologique de membres de la superfamille TGF-β dans une composition pharmaceutique. L'invention concerne également les utilisations des compositions pharmaceutiques en particulier en ce qui concerne la cicatrisation des lésions et la fibrose. De plus, l'invention concerne des médicaments de prévention ou de réduction de la douleur due à des injections.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NZ564906MXMX/a/2008/000661KR1020080031394IL188352EP1915169BRPI0613731-8
ZA2008/00281JP2009501200US20080176799CN101262877CA2614754AU2006268088
ID048.1192IN156/DELNP/2008