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1. (WO2007007040) 2 -HETEROCYCLYLOXYBENZOYL AMINO HETEROCYCLYL COMPOUNDS AS MODULATORS OF GLUCOKINASE FOR THE TREATMENT OF TYPE 2 DIABETES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/007040    International Application No.:    PCT/GB2006/002460
Publication Date: 18.01.2007 International Filing Date: 03.07.2006
IPC:
C07D 417/12 (2006.01), C07D 498/04 (2006.01), C07D 513/04 (2006.01), A61K 31/553 (2006.01), A61P 3/10 (2006.01), A61P 3/04 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; S-SE-151 85 Södertälje (SE) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
ASTRAZENECA UK LIMITED [GB/GB]; 15 Stanhope Gate, London Greater London W1K 1LN (GB) (MG only).
MCKERRECHER, Darren [GB/GB]; (GB) (For US Only).
PIKE, Kurt, Gordon [GB/GB]; (GB) (For US Only).
WARING, Michael, James [GB/GB]; (GB) (For US Only)
Inventors: MCKERRECHER, Darren; (GB).
PIKE, Kurt, Gordon; (GB).
WARING, Michael, James; (GB)
Agent: GLOBAL INTELLECTUAL PROPERTY; Astrazeneca AB, S-SE-151 85 Södertälje (SE)
Priority Data:
0514175.9 09.07.2005 GB
0516299.5 09.08.2005 GB
0523863.9 24.11.2005 GB
Title (EN) 2 -HETEROCYCLYLOXYBENZOYL AMINO HETEROCYCLYL COMPOUNDS AS MODULATORS OF GLUCOKINASE FOR THE TREATMENT OF TYPE 2 DIABETES
(FR) COMPOSÉS 2-HÉTÉROCYCLYLOXYBENZOYL AMINO HÉTÉROCYCLYLE EN TANT QUE MODULATEURS DE GLUCOKINASE POUR LE TRAITEMENT DU DIABÈTE DE TYPE 2
Abstract: front page image
(EN)Compounds of formula (I) wherein R1, HET-1 and HET-2 are as described in the specification, and their salts, are activators of glucokinase (GLK) and are thereby useful in the treatment of, for example, type 2 diabetes. Processes for preparing compounds of formula (I) are also described.
(FR)La présente invention concerne des composés de formule (I), R1, HET-1 et HET-2 étant tels que définis dans la description, ainsi que leurs sels, qui sont des activateurs de la glucokinase (GLK) et sont par conséquent utiles dans le traitement du diabète de type 2, par exemple. L’invention concerne également des procédés de préparation des composés de formule (I).
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)