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1. (WO2007006650) ASYMMETRIC REDUCTION OF 1,1,1-TRIFLUOROACETONE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/006650 International Application No.: PCT/EP2006/063621
Publication Date: 18.01.2007 International Filing Date: 28.06.2006
Chapter 2 Demand Filed: 10.01.2007
IPC:
C12P 7/04 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7
Preparation of oxygen-containing organic compounds
02
containing a hydroxy group
04
acyclic
Applicants:
F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 CH-4070 Basel, CH (AllExceptUS)
DOSWALD, Stephan [CH/CH]; CH (UsOnly)
HANLON, Steven Paul [GB/CH]; CH (UsOnly)
KUPFER, Ernst [CH/CH]; CH (UsOnly)
Inventors:
DOSWALD, Stephan; CH
HANLON, Steven Paul; CH
KUPFER, Ernst; CH
Agent:
POPPE, Regina; Grenzacherstrasse 124 CH-4070 Basel, CH
Priority Data:
05106261.008.07.2005EP
Title (EN) ASYMMETRIC REDUCTION OF 1,1,1-TRIFLUOROACETONE
(FR) REDUCTION ASYMETRIQUE DE 1,1,1-TRIFLUOROACETONE
Abstract:
(EN) The invention relates to a scalable biocatalytic process for the preparation of S- 1,1,1- trifluoro-2-propanol with a enantiomeric excess of > 99 % by asymmetric microbial reduction of 1,1,1-trifluoroacetone with Baker's yeast.
(FR) L'invention concerne un procédé biocatalytique modulable de préparation of S-1,1,1-trifluoro-2-propanol à excès énantiomérique > 99 %, par réduction microbienne asymétrique de 1,1,1-trifluoroacétone au moyen de levure de boulangerie.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
MXMX/a/2008/000260KR1020080018939IL188319EP1904640BRPI0614045JP2009501007
JP4219976CN101218350CA2614408AU2006268765IN122/CHENP/2008