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1. (WO2007006307) NOVEL SALTS OF FUMARIC ACID MONOALKYLESTERS AND THEIR PHARMACEUTICAL USE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/006307 International Application No.: PCT/DK2006/000402
Publication Date: 18.01.2007 International Filing Date: 07.07.2006
IPC:
C07C 55/02 (2006.01) ,C07C 69/593 (2006.01) ,A61K 31/194 (2006.01) ,A61K 31/195 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
55
Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
02
Dicarboxylic acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
69
Esters of carboxylic acids; Esters of carbonic or haloformic acids
52
Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
593
Dicarboxylic acid esters having only one carbon-to-carbon double bond
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
194
having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
195
having an amino group
Applicants:
ADITECH PHARMA AB [SE/SE]; Carlsgatan 12 A S-211 20 Malmö, SE (AllExceptUS)
NILSSON, Henrik [SE/DK]; DK (UsOnly)
ANDERSEN, Jens E.T. [DK/DK]; DK (UsOnly)
MÜLLER, Bernd, W. [DE/DE]; DE (UsOnly)
Inventors:
NILSSON, Henrik; DK
ANDERSEN, Jens E.T.; DK
MÜLLER, Bernd, W.; DE
Agent:
INSPICOS A/S; Bøge Allé 5 P.O. Box 45 DK-2970 Hørsholm, DK
Priority Data:
PA 2005 0100407.07.2005DK
Title (EN) NOVEL SALTS OF FUMARIC ACID MONOALKYLESTERS AND THEIR PHARMACEUTICAL USE
(FR) NOUVEAUX SELS DE MONOALKYLESTERS D'ACIDE FUMARIQUE ET LEUR UTILISATION PHARMACEUTIQUE
Abstract:
(EN) The present invention relates to novel amino acid salts of fumaric acid monoalkylesters. The salts are suitable for use as active substances in the treatment of e.g. psoriasis or other hyperproliferative, inflammatory or autoimmune disorders.
(FR) La présente invention concerne de nouveaux sels d'acides aminés de monoalkylesters d'acide fumarique. Ces sels sont appropriés pour une utilisation comme substances actives dans le traitement, par exemple, du psoriasis ou d'autres maladies hyperprolifératives, inflammatoires ou auto-immunes.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1915334US20080227847IN534/KOLNP/2008