WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2007006036) HYDROXYLATED FORMS OF ERGOSTEROLS AND ERGOCALCIFEROLS, DERIVATIVES THEREOF, METHODS OF PRODUCTION AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/006036    International Application No.:    PCT/US2006/026476
Publication Date: 11.01.2007 International Filing Date: 05.07.2006
IPC:
A61K 31/54 (2006.01), C07C 401/00 (2006.01)
Applicants: THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION [US/US]; 3 North Dunlap, Memphis, TN 38163 (US) (For All Designated States Except US)
Inventors: SLOMINSKI, Andrzej; (US).
TUCKEY, Robert; (US).
LI, Wei; (US).
ZBYTEK, Blazej; (US).
ZJAWIONY, Jordan; (US).
WORTSMAN, Jacobo; (US)
Agent: ADLER, Benjamin, A.; Adler & Associates, 8011 Candle Lane, Houston, TX 77071 (US)
Priority Data:
60/696,627 05.07.2005 US
60/801,216 17.05.2006 US
Title (EN) HYDROXYLATED FORMS OF ERGOSTEROLS AND ERGOCALCIFEROLS, DERIVATIVES THEREOF, METHODS OF PRODUCTION AND USES THEREOF
(FR) FORMES HYDROXYLEES D'ERGOSTEROLS ET D'ERGOCALCIFEROLS, DERIVES DE CEUX-CI, PROCEDES DE PRODUCTION ET UTILISATIONS DE CEUX-CI
Abstract: front page image
(EN)Provided herein is an enzymatic method of producing hydroxylated ergosterols and hydroxylated ergocalciferols using the cytochrome P450scc enzyme and/or the CYP27B1 enzyme and the hydroxylated compounds so produced. Also provided are methods of using the hydroxylated ergosterols and hydroxylated ergocalciferols to treat a tumor or other pathophysiologic condition.
(FR)Cette invention se rapporte à un procédé enzymatique de production d'ergostérols hydroxylés et d'ergocalciférols hydroxylés utilisant l'enzyme du cytochrome P450scc et/ou l'enzyme CYP27B1 et aux composés hydroxylés ainsi produits. Cette invention concerne également des procédés d'utilisation des ergostérols hydroxylés et des ergocalciférols hydroxylés pour traiter une tumeur ou un autre état pathologique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)