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1. (WO2007005940) COMBINATIONS OF ESZOPICLONE AND DIDESMETHYLSIBUTRAMINE, AND METHODS OF TREATMENT OF MENOPAUSE AND MOOD, ANXIETY, AND COGNITIVE DISORDERS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/005940 International Application No.: PCT/US2006/026146
Publication Date: 11.01.2007 International Filing Date: 05.07.2006
IPC:
A01N 43/58 (2006.01) ,A01N 43/60 (2006.01) ,A61K 31/495 (2006.01) ,A61K 31/50 (2006.01)
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
43
Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
48
having rings with two nitrogen atoms as the only ring hetero atoms
58
1,2-Diazines; Hydrogenated 1,2-diazines
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
43
Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
48
having rings with two nitrogen atoms as the only ring hetero atoms
60
1,4-Diazines; Hydrogenated 1,4-diazines
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
50
Pyridazines; Hydrogenated pyridazines
Applicants:
SEPRACOR INC. [US/US]; 84 Waterford Drive Marlborough, Massachusetts 01752, US (AllExceptUS)
CARON, Judy [US/US]; US (UsOnly)
WESSEL, Thomas [US/US]; US (UsOnly)
LALJI, Karim [US/US]; US (UsOnly)
VARNEY, Mark A. [US/US]; US (UsOnly)
Inventors:
CARON, Judy; US
WESSEL, Thomas; US
LALJI, Karim; US
VARNEY, Mark A.; US
Agent:
TIMMER, Edward; HESLIN ROTHENBERG FARLEY & MESITI P.C. 5 Columbia Circle Albany, New York 12203, US
Priority Data:
60/696,88006.07.2005US
Title (EN) COMBINATIONS OF ESZOPICLONE AND DIDESMETHYLSIBUTRAMINE, AND METHODS OF TREATMENT OF MENOPAUSE AND MOOD, ANXIETY, AND COGNITIVE DISORDERS
(FR) COMBINAISONS D'ESZOPICLONE ET DE DIDESMETHYLSIBUTRAMINE, METHODES DE TRAITEMENT DE LA MENOPAUSE, DE L'HUMEUR, DE L'ANXIETE ET DES TROUBLES DE LA CONNAISSANCE
Abstract:
(EN) One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is didesmethylsibutramine or (S)-didesmethylsibutramine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders.
(FR) Un aspect de la présente invention concerne des compositions pharmaceutiques contenant au moins deux agents actifs qui, lorsqu'ils sont pris ensemble, peuvent être utilisés pour traiter, par exemple, la ménopause, les troubles de l'humeur, les troubles anxieux ou les troubles de la connaissance. Le premier constituant de la composition pharmaceutique est un eszopiclone sédatif. Le deuxième constituant de la composition pharmaceutique est la didesméthylsibutramine ou (S)-didesméthylsibutramine. Cette invention porte également sur une méthode de traitement de la ménopause, de la périménopause, des troubles de l'humeur, des troubles anxieux et des troubles de la connaissance.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)