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Machine translation
1. (WO2007005766) GENOMIC NUCLEIC ACID SEQUENCE FOR CYANOVIRIN-N AND SIGNAL PEPTIDE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/005766    International Application No.:    PCT/US2006/025869
Publication Date: 11.01.2007 International Filing Date: 30.06.2006
IPC:
C07K 14/195 (2006.01), A61K 38/16 (2006.01), A61K 38/00 (2006.01), A61K 48/00 (2006.01), C12N 15/31 (2006.01)
Applicants: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; Office Of Technology Transfer, 6011 Executive Boulevard, Suite 325, Rockville, Maryland 20852 (US) (For All Designated States Except US).
GRONENBORN, Angela, M. [US/US]; (US) (For US Only)
Inventors: GRONENBORN, Angela, M.; (US)
Agent: GASE, John, L.; Leydig, Voit & Mayer, Ltd., Two Prudential Plaze, Suite 4900, 180 N. Stetson Avenue, Chicago, Illinois 60601-6780 (US)
Priority Data:
60/696,599 05.07.2005 US
Title (EN) GENOMIC NUCLEIC ACID SEQUENCE FOR CYANOVIRIN-N AND SIGNAL PEPTIDE THEREOF
(FR) SEQUENCE D'ACIDE NUCLEIQUE GENOMIQUE DE LA CYANOVIRINE-N ET DE SON PEPTIDE SIGNAL
Abstract: front page image
(EN)An isolated or purified nucleic acid encoding a CV-N signal peptide, wherein the CV-N signal peptide comprises an amino acid sequence that has about 50% or greater sequence identity to SEQ ID NO: 2, and an isolated or purified nucleic acid comprising a genomic nucleic acid sequence encoding a cyanovirin-N (CV-N) polypeptide, are provided herein. Also provided are vectors and cells comprising the aforementioned nucleic acids, a method of producing a polypeptide, and a method of inhibiting a viral infection in a mammal. A polypeptide comprising the CV-N signal peptide also is provided.
(FR)La présente invention concerne un acide nucléique isolé ou purifié codant pour un peptide signal de CV-N, caractérisé en ce que le peptide signal de CV-N comprend une séquence d'acides aminés qui présente une identité de séquence avec SEQ ID NO: 2 d'environ 50% ou plus, et un acide nucléique isolé ou purifié comprenant une séquence d'acide nucléique génomique codant pour un polypeptide cyanovirine-N (CV-N). L'invention concerne également des vecteurs et des cellules comprenant les acides nucléiques susmentionnés, un procédé de production d'un polypeptide et un procédé d'inhibition d'une infection virale chez un mammifère. L'invention concerne en outre un polypeptide comprenant le peptide signal de CV-N.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)