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1. (WO2007005645) MATERIALS AND METHODS FOR THE GENERATION OF FULLY 2'-MODIFIED NUCLEIC ACID TRANSCRIPTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/005645 International Application No.: PCT/US2006/025653
Publication Date: 11.01.2007 International Filing Date: 30.06.2006
IPC:
C07K 14/00 (2006.01) ,C07H 21/04 (2006.01) ,C12P 21/06 (2006.01) ,A61K 38/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
04
with deoxyribosyl as saccharide radical
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21
Preparation of peptides or proteins
06
produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
Applicants:
ARCHEMIX CORP. [US/US]; 300 Third Street First Floor Cambridge, MA 02142, US (AllExceptUS)
CLOAD, Sharon, T. [US/US]; US (UsOnly)
DIENER, John, L. [US/US]; US (UsOnly)
KEEFE, Anthony, Dominic [GB/US]; US (UsOnly)
THOMPSON, Kristin [US/US]; US (UsOnly)
WANG, Chunhua; US (UsOnly)
Inventors:
CLOAD, Sharon, T.; US
DIENER, John, L.; US
KEEFE, Anthony, Dominic; US
THOMPSON, Kristin; US
WANG, Chunhua; US
Agent:
ELRIFI, Ivor, R.; MINTZ, LEVIN, COHN, FERRIS, GLOVSKY AND POPEO PC One Financial Center Boston, MA 02111, US
Priority Data:
60/696,29230.06.2005US
Title (EN) MATERIALS AND METHODS FOR THE GENERATION OF FULLY 2'-MODIFIED NUCLEIC ACID TRANSCRIPTS
(FR) MATERIAUX ET PROCEDES POUR LA GENERATION DE TRANSCRIPTIONS D'ACIDE NUCLEIQUES MODIFIEE EN 2'
Abstract:
(EN) Materials and methods are provided for producing aptamer therapeutics having fully modified nucleotide triphosphates incorporated into their sequence.
(FR) La présente invention concerne des matériaux et procédés destinés à la production de produits thérapeutiques aptamères dans la séquence desquels sont incorporés des triphosphates nucléotidiques totalement modifiés
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NZ564918MXMX/a/2007/016561KR1020080025181IL188206EP1907590BRPI0611701-5
JP2009504139CN101495504CA2613442AU2006265896IN57/KOLNP/2008