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1. (WO2007005510) N-HETEROARYLPIPERAZINYL UREAS AS MODULATORS OF FATTY ACID AMIDE HYDROLASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/005510    International Application No.:    PCT/US2006/025343
Publication Date: 11.01.2007 International Filing Date: 28.06.2006
IPC:
C07D 285/08 (2006.01), C07D 417/12 (2006.01), C07D 417/04 (2006.01), A61K 31/497 (2006.01), A61K 31/506 (2006.01), A61P 25/22 (2006.01), A61P 29/00 (2006.01)
Applicants: JANSSEN PHARMACEUTICA N.V. [BE/BE]; Turnhoutsweg 30, B-2340 Beerse (BE) (For All Designated States Except US).
APODACA, Richard [US/US]; (US) (For US Only).
BREITENBUCHER, J., Guy [US/US]; (US) (For US Only).
PATTABIRAMAN, Kanaka [IN/US]; (US) (For US Only).
SEIERSTAD, Mark [US/US]; (US) (For US Only).
XIAO, Wei [US/US]; (US) (For US Only)
Inventors: APODACA, Richard; (US).
BREITENBUCHER, J., Guy; (US).
PATTABIRAMAN, Kanaka; (US).
SEIERSTAD, Mark; (US).
XIAO, Wei; (US)
Agent: EVANS, Linda, S.; PATENT LAW DEPT., JOHNSON & JOHNSON, One Johnson & Johnson Plaza, New Brunswick, NJ 08933 (US)
Priority Data:
60/696,166 30.06.2005 US
Title (EN) N-HETEROARYLPIPERAZINYL UREAS AS MODULATORS OF FATTY ACID AMIDE HYDROLASE
(FR) UREES N-HETEROARYLPIPERAZINYLE EN TANT QUE MODULATEURS DE L'HYDROLASE DE L'AMIDE D'ACIDE GRAS
Abstract: front page image
(EN)Certain /V-heteroarylpiperazinyl urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).
(FR)L'invention concerne certains composés d'urée N-hétéroarylpipérazinyle, utiles en tant qu'inhibiteurs de la FAAH. De tels composés peuvent être utilisés dans des compositions pharmaceutiques et dans des méthodes de traitement de maladies, de troubles, et de pathologies médiées par l'activité de l'hydrolase de l'amide d'acide gras (FAAH). Ainsi ces composés peuvent être administrés pour traiter, par exemple, l'anxiété, la douleur, l'inflammation, les troubles du sommeil, les troubles de l'alimentation, ou les troubles du mouvement (tels que la sclérose en plaques).
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)