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1. (WO2007005491) HYDRAZIDE CONJUGATES AS IMAGING AGENTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/005491 International Application No.: PCT/US2006/025298
Publication Date: 11.01.2007 International Filing Date: 28.06.2006
IPC:
A61K 51/08 (2006.01) ,A61K 49/00 (2006.01) ,C07K 1/13 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
02
characterised by the carrier
04
Organic compounds
08
Peptides, e.g. proteins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49
Preparations for testing in vivo
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
13
Labelling of peptides
Applicants:
BRISTOL-MYERS SQUIBB PHARMA COMPANY [US/US]; Route 206 And Province Line Road Princeton, New Jersey 08543-4000, US (AllExceptUS)
HARRIS, Thomas, D. [US/US]; US (UsOnly)
ROBINSON, Simon, P. [GB/US]; US (UsOnly)
CESATI, Richard, R. [US/US]; US (UsOnly)
YALAMANCHILI, Padmaja [US/US]; US (UsOnly)
Inventors:
HARRIS, Thomas, D.; US
ROBINSON, Simon, P.; US
CESATI, Richard, R.; US
YALAMANCHILI, Padmaja; US
Agent:
MINGO, Pamela A., Ph. D. ; Bristol-Myers Squibb Company P.O. Box 4000 Princeton, New Jersey 08543-4000, US
Priority Data:
60/695,49630.06.2005US
Title (EN) HYDRAZIDE CONJUGATES AS IMAGING AGENTS
(FR) CONJUGUES D'HYDRAZIDE EN TANT QU'AGENTS D'IMAGERIE
Abstract:
(EN) The present disclosure is directed to diagnostic agents. More specifically, the disclosure is directed to compounds, diagnostic agents, compositions, and kits for detecting and/or imaging and/or monitoring a pathological disorder associated with coronary plaque, carotid plaque, aortic plaque, plaque of the arterial vessel, aneurism, vasculitis, and other diseases of the arterial wall. In addition, the disclosure is directed to methods of detecting and/or imaging and/or monitoring changes in the arterial wall, including expansive and constrictive remodeling, total vessel wall area, internal lumen size, and exterior artery perimeter.
(FR) La présente invention concerne des agents diagnostiques. Plus spécifiquement, cette invention a pour objet des composés, des agents diagnostiques, des compositions et des kits de détection et/ou d'imagerie et/ou de surveillance d'un trouble pathologique associé à une plaque coronaire, une plaque de la carotide, une plaque de l'aorte, une plaque d'artère, un anévrisme, une vascularite et d'autres troubles de la paroi artérielle. En outre, ladite invention a trait à des méthodes de détection et/ou d'imagerie et/ou de surveillance de modifications de la paroi artérielle, y compris, un remodelage expansif et constrictif, une zone de paroi vasculaire entière, une taille de lumière interne et un périmètre d'artère externe.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NO20076423KR1020080022588EP1896086JP2009500410CN101252954CA2613439
AU2006266074IN10111/DELNP/2007