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Machine translation
1. (WO2007005404) AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR ß-SECRETASE MODULATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/005404    International Application No.:    PCT/US2006/024912
Publication Date: 11.01.2007 International Filing Date: 26.06.2006
IPC:
C07D 401/04 (2006.01), C07D 401/14 (2006.01), C07D 409/14 (2006.01), C07D 405/14 (2006.01), C07D 403/04 (2006.01), C07D 403/14 (2006.01), A61K 31/4439 (2006.01), A61K 31/506 (2006.01), A61P 25/28 (2006.01)
Applicants: WYETH [US/US]; Five Giralda Farms, Madison, New Jersey 07940 (US) (For All Designated States Except US).
ZHOU, Ping [US/US]; (US) (For US Only).
MALAMAS, Michael Sotirios [US/US]; (US) (For US Only).
LI, Yanfang [CN/US]; (US) (For US Only).
ROBICHAUD, Albert Jean [US/US]; (US) (For US Only).
QUAGLIATO, Dominick Anthony [US/US]; (US) (For US Only)
Inventors: ZHOU, Ping; (US).
MALAMAS, Michael Sotirios; (US).
LI, Yanfang; (US).
ROBICHAUD, Albert Jean; (US).
QUAGLIATO, Dominick Anthony; (US)
Agent: LENCES, Barbara, L.; Wyeth, Patent Law Department, Five Giralda Farms, Madison, New Jersey 07940, (US)
Priority Data:
60/695,305 30.06.2005 US
Title (EN) AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR ß-SECRETASE MODULATION
(FR) DÉRIVÉS D'IMIDAZOLONE PORTANT UN GROUPEMENT HÉTÉROARYLE À 6 CHAÎNONS EN POSITION 5 ET UN GROUPEMENT AMINO, ET LEUR EMPLOI DANS LA RÉGULATION DE LA &bgr;-SECRÉTASE
Abstract: front page image
(EN)The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I. The present invention also provides methods for the use thereof to inhibit ß-secretase (BACE) and treat ß-amyloid deposits and neurofibrillary tangles
(FR)La présente invention décrit un dérivé de 2-amino-5-hétéroaryle-5-phénylimidazolone de formule I. La présente invention décrit également des méthodes d'emploi de ce dérivé dans l'inhibition de la &bgr;-secrétase (BACE) et le traitement de dépôts de type &bgr;-amyloïdes et d'enchevêtrements neurofibrillaires.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)