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1. (WO2007004776) COMPOSITIONS FOR INDUCING THE DIFFERENTIATION OF STEM CELLS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/004776    International Application No.:    PCT/KR2005/003921
Publication Date: 11.01.2007 International Filing Date: 18.11.2005
IPC:
C12N 5/0793 (2010.01)
Applicants: KIM, Sung Su [KR/KR]; (KR) (For US Only).
NOH, Yoo Hun [KR/KR]; (KR) (For US Only).
KANG, Yong Koo [KR/KR]; (KR) (For US Only).
KIM, Yong Sik [KR/KR]; (KR) (For US Only).
LEE, Hyun Jung [KR/KR]; (KR) (For US Only).
LEE, Do Yeon [KR/KR]; (KR) (For US Only).
YUN, Ji Young [KR/KR]; (KR) (For US Only).
LEE, In Sook [KR/KR]; (KR) (For US Only).
LEE, Won Bok [KR/KR]; (KR) (For US Only).
LEE, Moo Yeol [KR/KR]; (KR) (For US Only).
KIM, Dae Kyong [KR/KR]; (KR) (For US Only)
Inventors: KIM, Sung Su; (KR).
NOH, Yoo Hun; (KR).
KANG, Yong Koo; (KR).
KIM, Yong Sik; (KR).
LEE, Hyun Jung; (KR).
LEE, Do Yeon; (KR).
YUN, Ji Young; (KR).
LEE, In Sook; (KR).
LEE, Won Bok; (KR).
LEE, Moo Yeol; (KR).
KIM, Dae Kyong; (KR)
Agent: YANG, Boo-Hyun; 4th Fl. Oksan Bldg., 1627-10, Bongcheon-7-dong, Gwanak-gu, Seoul 151-818 (KR)
Priority Data:
10-2005-0060741 06.07.2005 KR
Title (EN) COMPOSITIONS FOR INDUCING THE DIFFERENTIATION OF STEM CELLS AND USES THEREOF
(FR) COMPOSITIONS PERMETTANT D'INDUIRE LA DIFFERENCIATION DE CELLULES SOUCHES ET UTILISATIONS DE CELLES-CI
Abstract: front page image
(EN)The present invention relates to the differentiation of stem cells, a composition for inducing stem cell differentiation comprising N-acetylcysteine as an active ingredient, a method for inducing stem cell differentiation and a pharmaceutical composition for treating or preventing neuronal diseases comprising neuronal cells differentiated from stem cells. The present invention permits to produce differentiated cells (preferably, neuronal cells, more preferably dopaminergic neuronal cells) from stem cells in an effective manner. Neuronal cells produced by this invention are very useful in the realm of therapeutics for various neuronal diseases caused by neuronal cell injury.
(FR)L'invention concerne la différenciation de cellules souches, une composition permettant d'induire la différenciation de cellules souches comprenant de la N-acétylcystéïne en tant qu'ingrédient actif, un procédé permettant d'induire la différenciation de cellules souches et une composition pharmaceutique pour le traitement ou la prévention de maladies neuronales dans lesquelles des cellules neuronales sont différenciées par rapport à des cellules souches. L'invention permet de produire des cellules différenciées (de préférence, des cellules neuronales, idéalement des cellules neuronales dopaminergiques) par rapport à des cellules souches de manière efficace. Les cellules neuronales obtenues selon l'invention s'avèrent particulièrement utiles dans le domaine des agents thérapeutiques pour diverses maladies neuronales provoquées par une lésion des cellules neuronales.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: Korean (KO)