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1. (WO2007003944) COMPOUNDS FOR IMAGING AND THERAPY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/003944 International Application No.: PCT/GB2006/002488
Publication Date: 11.01.2007 International Filing Date: 05.07.2006
IPC:
G01N 33/58 (2006.01) ,A61K 49/00 (2006.01) ,A61K 51/04 (2006.01) ,C07D 213/77 (2006.01) ,C07D 277/66 (2006.01) ,A61P 35/00 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58
involving labelled substances
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49
Preparations for testing in vivo
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
02
characterised by the carrier
04
Organic compounds
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
213
Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02
having three double bonds between ring members or between ring members and non-ring members
04
having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
60
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
72
Nitrogen atoms
76
to which a second hetero atom is attached
77
Hydrazine radicals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
277
Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
60
condensed with carbocyclic rings or ring systems
62
Benzothiazoles
64
with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
66
with aromatic rings or ring systems directly attached in position 2
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
ISIS INNOVATION LIMITED [GB/GB]; Ewert House Ewert Place Summertown Oxford OX2 7SG, GB (AllExceptUS)
DILWORTH, Jonathan, Robin [GB/GB]; GB (UsOnly)
PEACH, Josephine, Mary [GB/GB]; GB (UsOnly)
HESLOP, Julia, May [NZ/GB]; GB (UsOnly)
DONNELLY, Paul, Stephen [AU/AU]; AU (UsOnly)
Inventors:
DILWORTH, Jonathan, Robin; GB
PEACH, Josephine, Mary; GB
HESLOP, Julia, May; GB
DONNELLY, Paul, Stephen; AU
Agent:
KEEN, Celia, Mary ; J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ, GB
Priority Data:
0513812.805.07.2005GB
Title (EN) COMPOUNDS FOR IMAGING AND THERAPY
(FR) COMPOSES D'IMAGERIE ET DE TRAITEMENT
Abstract:
(EN) A metal complex of formula (III) wherein: M is a transition metal and Al, A2, X, X', Y, Ll', Rl' and R2' are as defined herein, is useful in medical imaging and therapy.
(FR) L'invention concerne un complexe métallique représenté par la formule (III), dans laquelle M représente un métal de transition et A1, A2, X, X', Y, L1', R1' et R2' sont tels que définis dans la demande. Le complexe est utile dans l'imagerie médicale et comme traitement.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
US20110098353