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1. (WO2007003609) TREATMENT OF LIVER CIRRHOSIS AND ITS COMPLICATIONS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/003609 International Application No.: PCT/EP2006/063762
Publication Date: 11.01.2007 International Filing Date: 30.06.2006
IPC:
A61K 39/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
Applicants:
VIB VZW [BE/BE]; Rijvisschestraat 120 B-9052 Zwijnaarde, BE (AllExceptUS)
D. COLLEN RESEARCH FOUNDATION VZW [BE/BE]; Onderwijs & Navorsing, Campus Gasthuisbe K.U. Leuven Herestraat 49 B-3000 Leuven, BE (AllExceptUS)
UNIVERSITEIT GENT [BE/BE]; Sint-Pietersnieuwstraat 25 B-9000 Gent, BE (AllExceptUS)
CARMELIET, Peter [BE/BE]; BE (UsOnly)
COLLE, Isabelle [BE/BE]; BE (UsOnly)
GEERTS, Anja [BE/BE]; BE (UsOnly)
Inventors:
CARMELIET, Peter; BE
COLLE, Isabelle; BE
GEERTS, Anja; BE
Common
Representative:
VIB VZW; Rijvisschestraat 120 B-9052 Zwijnaarde, BE
Priority Data:
05105923.630.06.2005EP
Title (EN) TREATMENT OF LIVER CIRRHOSIS AND ITS COMPLICATIONS
(FR) TRAITEMENT DE LA CIRRHOSE HEPATIQUE ET DE SES COMPLICATIONS
Abstract:
(EN) The present invention relates to the field of liver diseases, more particularly to the field of portal hypertension and liver cirrhosis. The invention relates to the use of molecules which can inhibit the binding of placental growth factor (PIGF) to its receptor (VEGFR-1 ), such as monoclonal antibodies, for the manufacture of a medicament to treat liver cirrhosis, portal hypertension and its complications.
(FR) La présente invention se rapporte au domaine des maladies hépatiques, plus particulièrement au domaine de l'hypertension portale et de la cirrhose hépatique. L'invention concerne l'utilisation de molécules pouvant inhiber la liaison du facteur de croissance placentaire (PIGF) à son récepteur (VEGFR-1), telles que des anticorps monoclonaux, pour la fabrication d'un médicament destiné à traiter la cirrhose hépatique, l'hypertension portale et leurs complications.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1904095US20090111974