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1. (WO2007003536) SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/003536    International Application No.:    PCT/EP2006/063611
Publication Date: 11.01.2007 International Filing Date: 28.06.2006
IPC:
C07D 409/14 (2006.01), C07D 409/12 (2006.01), C07D 487/04 (2006.01), C07D 413/04 (2006.01), C07D 417/14 (2006.01), C07D 471/04 (2006.01), A61K 31/55 (2006.01), A61P 29/00 (2006.01), A61P 35/00 (2006.01), A61P 9/00 (2006.01)
Applicants: BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE/DE]; Binger Str. 173, 55216 Ingelheim Am Rhein (DE) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG [DE/DE]; Binger Str. 173, 55216 Ingelheim Am Rhein (DE) (DE only).
PRIEPKE, Henning [DE/DE]; (DE) (For US Only).
DAHMANN, Georg [DE/DE]; (DE) (For US Only).
GERLACH, Kai [DE/DE]; (DE) (For US Only).
PFAU, Roland [DE/DE]; (DE) (For US Only).
WIENEN, Wolfgang [DE/DE]; (DE) (For US Only).
SCHULER-METZ, Annette [DE/DE]; (DE) (For US Only).
HANDSCHUH, Sandra [DE/DE]; (DE) (For US Only).
NAR, Herbert [DE/DE]; (DE) (For US Only)
Inventors: PRIEPKE, Henning; (DE).
DAHMANN, Georg; (DE).
GERLACH, Kai; (DE).
PFAU, Roland; (DE).
WIENEN, Wolfgang; (DE).
SCHULER-METZ, Annette; (DE).
HANDSCHUH, Sandra; (DE).
NAR, Herbert; (DE)
Agent: HAMMANN, Heinz; Binger Str. 173, 55216 Ingelheim Am Rhein (DE)
Priority Data:
05014270.2 30.06.2005 EP
Title (DE) SUBSTITUIERTE GLYCINAMIDE MIT ANTITHROMBOTISCHER UND FAKTOR XA-INHIBIERENDER WIRKUNG
(EN) SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT
(FR) GLYCINAMIDES SUBSTITUES A EFFET ANTITHROMBOTIQUE ET INHIBANT LE FACTEUR XA
Abstract: front page image
(DE)Gegenstand der vorliegenden Erfindung sind neue substituierte Glycinamide der allgemeinen Formel (I), in denen D, M, R3, R4 und R5 wie in der Beschreibung definiert sind, deren Tautomere, deren Enantiomere, deren Diastereomere, deren Gemische und deren Salze, insbesondere deren physiologisch verträgliche Salze mit anorganischen oder organischen Säuren oder Basen, welche wertvolle Eigenschaften aufweisen.
(EN)The invention relates to novel substituted glycinamides of general formula (I), wherein D, M, R3, R4, and R5 are defined as indicated in the description, the tautomers, enantiomers, diastereomers, mixtures, and salts thereof, especially the physiologically acceptable salts thereof with inorganic or organic acids or bases, which are provided with valuable characteristics.
(FR)L'invention a pour objet de nouveaux glycinamides substitués de formule générale (I), dans laquelle D, M, R3, R4 et R5 sont tels que définis dans la description, ainsi que leurs tautomères, leurs énantiomères, leurs diastéréomères, leurs mélanges et leurs sels, en particulier leurs sels physiologiquement compatibles avec des acides ou des bases inorganiques ou organiques, ces nouveaux composés présentant des propriétés précieuses.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)