Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2007003426) ANTI-CCR7 RECEPTOR ANTIBODIES FOR THE TREATMENT OF CANCER
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/003426 International Application No.: PCT/EP2006/006556
Publication Date: 11.01.2007 International Filing Date: 05.07.2006
Chapter 2 Demand Filed: 04.05.2007
IPC:
A61K 39/395 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
UNIVERSIDAD AUTÓNOMA DE MADRID [ES/ES]; Einstein, 3 E-28049 Madrid, ES (AllExceptUS)
MUÑOZ CALLEJA, Cecilia [ES/ES]; ES (UsOnly)
ALFONSO PÉREZ, Manuel Jesús [ES/ES]; ES (UsOnly)
LÓPEZ GIRAL, Sonia [ES/ES]; ES (UsOnly)
Inventors:
MUÑOZ CALLEJA, Cecilia; ES
ALFONSO PÉREZ, Manuel Jesús; ES
LÓPEZ GIRAL, Sonia; ES
Agent:
ARIAS SANZ, Juan; ABG Patentes, S.L. Avenida de Burgos, 16D Edificio Euromor E-28036 Madrid, ES
Priority Data:
PCT/EP2005/00737106.07.2005EP
Title (EN) ANTI-CCR7 RECEPTOR ANTIBODIES FOR THE TREATMENT OF CANCER
(FR) ANTICORPS ANTI-RECEPTEUR CCR7 POUR TRAITER LE CANCER
Abstract:
(EN) Antibodies, or antigen-binding fragment thereof, which bind to a CCR7 receptor are capable of selectively killing, impairing migration and/or blocking dissemination of tumour cells expressing a CCR7 receptor. Use of said antibodies for killing or for inducing apoptosis of said tumour is disclosed, thus providing an alternative therapy for treatment of cancer which tumour cells express a CCR7 receptor.
(FR) Selon l'invention, des anticorps ou des fragments de liaison à l'antigène de ceux-ci, qui se lient à un récepteur CCR7, sont capables de détruire, d'empêcher la migration et/ou de bloquer la dissémination, de manière sélective, de cellules tumorales qui expriment un récepteur CCR7. L'invention a également pour objet l'utilisation de ces anticorps pour détruire ou pour induire l'apoptose des cellules tumorales, ce qui permet d'obtenir une thérapie alternative pour traiter un cancer dont les cellules tumorales expriment un récepteur CCR7.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
MXMX/a/2008/000154KR1020080030655IL188594EP1904102JP2008545000RU02404808
US20090123483CN101257923CA2614080AU2006265281DK1904102IN97/KOLNP/2008