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1. (WO2007003330) PHARMACEUTICAL DOSAGE FORM CONTAINING AN ACTIVE PRINCIPLE COMBINATION OF NIFEDIPINE AND/OR NISOLDIPINE AND OF AN ANGIOTENSIN II ANTAGONIST
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/003330 International Application No.: PCT/EP2006/006293
Publication Date: 11.01.2007 International Filing Date: 29.06.2006
IPC:
A61P 9/00 (2006.01) ,A61K 31/4422 (2006.01) ,A61K 31/4184 (2006.01) ,A61K 31/4178 (2006.01) ,A61K 45/06 (2006.01) ,A61K 9/44 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4422
1,4-Dihydropyridines, e.g. nifedipine, nicardipine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4164
1,3-Diazoles
4184
condensed with carbocyclic rings, e.g. benzimidazoles
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4164
1,3-Diazoles
4178
not condensed and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
44
printed, embossed, grooved, or perforated
Applicants:
BAYER HEALTHCARE AG [DE/DE]; 51368 Leverkusen, DE (AllExceptUS)
OHM, Andreas [DE/DE]; DE (UsOnly)
BENKE, Klaus [DE/DE]; DE (UsOnly)
TINEL, Hanna [DE/DE]; DE (UsOnly)
HÜTTER, Joachim [DE/DE]; DE (UsOnly)
Inventors:
OHM, Andreas; DE
BENKE, Klaus; DE
TINEL, Hanna; DE
HÜTTER, Joachim; DE
Common
Representative:
BAYER HEALTHCARE AG; Law and Patents Patents and Licensing 51368 Leverkusen, DE
Priority Data:
102005031577.106.07.2005DE
Title (DE) PHARMAZEUTISCHE DARREICHUNGSFORMEN ENTHALTEND EINE WIRKSTOFFKOMBINATION VON NIFEDIPIN UND/ODER NISOLDIPIN UND EINEM ANGIOTENSIN-II ANTAGONISTEN
(EN) PHARMACEUTICAL DOSAGE FORM CONTAINING AN ACTIVE PRINCIPLE COMBINATION OF NIFEDIPINE AND/OR NISOLDIPINE AND OF AN ANGIOTENSIN II ANTAGONIST
(FR) FORME DOSIFIEE PHARMACEUTIQUE CONTENANT UNE ASSOCIATION DE PRINCIPES ACTIFS DE NIFEDIPINE ET/OU DE NISOLDIPINE ET UN ANTAGONISTE DE L'ANGIOTENSINE-II
Abstract:
(DE) Die vorliegende Erfindung betrifft eine pharmazeutische Darreichungsform enthaltend eine Wirkstoffkombination von Nifedipin oder Nisoldipin und mindestens einem Angiotensin-II Antagonisten, dadurch gekennzeichnet, dass die Wirkstoffkombination im Körper kontrolliert (modifiziert) freigegeben wird sowie Verfahren zu ihrer Herstellung, ihre Anwendung als Arzneimittel, ihre Verwendung zur Prophylaxe, Sekundärprophylaxe und/oder Behandlung von Erkrankungen sowie ihre Verwendung zur Herstellung eines Arzneimittels zur Prophylaxe, Sekundärprophylaxe und/oder Behandlung von Erkrankungen.
(EN) The invention relates to a pharmaceutical dosage form containing an active principle combination of nifedipine and/or nisoldipine and of at least one angiotensin II antagonist, characterized in that the active principle combination is released in the body in a controlled (modified) manner, and to methods for the production thereof, their use as medicaments, their use for the prophylaxis, secondary prophylaxis and/or treatment of diseases as well as to their use for producing a medicament for the prophylaxis, secondary prophylaxis and/or treatment of diseases.
(FR) La présente invention concerne une forme dosifiée pharmaceutique contenant une association de principes actifs de Nifédipine ou Nisoldipine et au moins un antagoniste de l'angiotensine-II. L'invention est caractérisée en ce que l'association de principes actifs est libérée de manière contrôlée (modifiée) dans l'organisme. L'invention concerne également son procédé de production, son utilisation en tant que médicament, son utilisation pour la prophylaxie, la prophylaxie secondaire et/ou le traitement de maladies ainsi que son utilisation pour produire un médicament destiné à la prophylaxie, la prophylaxe secondaire et/ou le traitement de maladies.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)
Also published as:
MXMX/a/2008/000275KR1020080031382IL188583EP1904180BRPI0612681-2ZA2008/00176
JP2009500361US20090214664CN101257946CA2614085AU2006265367IN515/DELNP/2008