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1. (WO2007002722) SYNTHESIS OF ANASTROZOLE AND PURIFICATION OF ONE OF ITS INTERMEDIATE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/002722    International Application No.:    PCT/US2006/025095
Publication Date: 04.01.2007 International Filing Date: 27.06.2006
IPC:
C07D 249/08 (2006.01), A61K 31/4196 (2006.01), A61P 35/00 (2006.01), C07C 255/33 (2006.01)
Applicants: SICOR, INC. [US/US]; 19 Hughes, Irvine, CA 92618 (US) (For All Designated States Except US).
PONTIROLI, Alessandro [IT/IT]; (IT) (For US Only).
CASALONE, Roberto [IT/IT]; (IT) (For US Only)
Inventors: PONTIROLI, Alessandro; (IT).
CASALONE, Roberto; (IT)
Agent: BRAINARD, Charles, R.; Kenyon & Kenyon LLP, One Broadway, New York, NY 10004-1050 (US)
Priority Data:
60/694,528 27.06.2005 US
Title (EN) SYNTHESIS OF ANASTROZOLE AND PURIFICATION OF ONE OF ITS INTERMEDIATE
(FR) PROCÉDÉ DE PURIFICATION D'UN INTERMÉDIAIRE DE L'ANASTROZOLE
Abstract: front page image
(EN)The invention is directed to processes for purifying the Anastrozole intermediate, 3,5-bis(2-cyanoisopropyl)toluene, processes for producing Anastrozole, processes for preparing Anastrozole pharmaceutical compositions, and Anastrozole and Anastrozole pharmaceutical compositions prepared with the processes of the invention.
(FR)La présente invention concerne des procédés de purification du 3,5-bis(2-cyanoisopropyl)toluène, intermédiaire de l'Anastrozole, des procédés de production de l'Anastrozole, des procédés d'élaboration de préparations pharmaceutiques contenant de l'Anastrozole, ainsi que de l'Anastrozole et des préparations pharmaceutiques contenant de l'Anastrozole préparés par le biais des procédés selon l'invention.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)