WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2007002462) CRYSTALLINE FORMS OF MC4R AGONIST AND PROCESS FOR SYNTHESIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/002462    International Application No.:    PCT/US2006/024573
Publication Date: 04.01.2007 International Filing Date: 23.06.2006
IPC:
A61K 31/445 (2006.01), C07D 401/06 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, NJ 07065-0907 (US) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
CALABRIA, Ralph [US/US]; (US) (For US Only).
CHENG, Yu [CN/US]; (US) (For US Only).
FERLITA, Russell, R. [US/US]; (US) (For US Only).
KAMALI, Ashkan [US/US]; (US) (For US Only).
MURRY, Jerry, A. [US/US]; (US) (For US Only).
MATHRE, David [US/US]; (US) (For US Only).
PERESYPKIN, Andrey, V. [RU/US]; (US) (For US Only).
THOMPSON, Karen [US/US]; (US) (For US Only).
WANG, Jian [US/US]; (US) (For US Only).
WENSLOW, Robert, M. [US/US]; (US) (For US Only)
Inventors: CALABRIA, Ralph; (US).
CHENG, Yu; (US).
FERLITA, Russell, R.; (US).
KAMALI, Ashkan; (US).
MURRY, Jerry, A.; (US).
MATHRE, David; (US).
PERESYPKIN, Andrey, V.; (US).
THOMPSON, Karen; (US).
WANG, Jian; (US).
WENSLOW, Robert, M.; (US)
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue, Rahway, NJ 07065-0907 (US)
Priority Data:
60/694,488 27.06.2005 US
Title (EN) CRYSTALLINE FORMS OF MC4R AGONIST AND PROCESS FOR SYNTHESIS
(FR) FORMES CRISTALLINES DE L'AGONISTE MC4R ET PROCEDE DE SYNTHESE
Abstract: front page image
(EN)The present invention relates to a process for producing N-{(1S)-1-[2-(1-{[(3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl]carbonyl} piperidin-4-yl)-5-chlorophenyl]ethyl}acetamide, and novel crystalline salts, hydrates, solvates, and polymorphic forms thereof.
(FR)L'invention concerne un procédé pour produire N-{(1S)-1-[2-(1-{[(3S,4R)-1-tert-butyle-4-(2,4-difluorophényle)pyrrolidine-3-yle]carbonyle} pipéridine-4-yle)-5-chlorophényle]éthyel}acétamide, ainsi que des sels cristallins, des hydrates, des solvates et des formes polymorphes de ces éléments.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)