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1. WO2007002356 - METHODS AND COMPOSITIONS CONTAINING NATURAL FOLATES FOR PROTECTING AGAINST RADIATION DAMAGE

Publication Number WO/2007/002356
Publication Date 04.01.2007
International Application No. PCT/US2006/024415
International Filing Date 21.06.2006
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
415
1,2-Diazoles
A61K 31/415 (2006.01)
CPC
A23L 33/15
A61K 31/415
A61K 8/4953
A61Q 17/04
Applicants
  • SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION [US/US]; Csab 253 Mobile, AL 36688, US (AllExceptUS)
  • CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND [US/US]; 5700 Martin Luther King Jr. Way Oakland, CA 94609, US (AllExceptUS)
  • BAILEY, Steven, W. [US/US]; US (UsOnly)
  • AYLING, June, E. [US/US]; US (UsOnly)
  • OFFER, Tal [IL/IL]; IL (UsOnly)
  • LENTON, Kevin, J. [CA/CA]; CA (UsOnly)
Inventors
  • BAILEY, Steven, W.; US
  • AYLING, June, E.; US
  • OFFER, Tal; IL
  • LENTON, Kevin, J.; CA
Agents
  • ROGALSKYJ, Peter ; ROGALSKYJ & WEYAND LLP P.O. Box 44 Livonia, NY 14487-0044, US
Priority Data
60/692,40121.06.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND COMPOSITIONS CONTAINING NATURAL FOLATES FOR PROTECTING AGAINST RADIATION DAMAGE
(FR) METHODES ET COMPOSITIONS CONTENANT DES FOLATES NATURELS POUR PROTECTION CONTRE LES RADIOLESIONS
Abstract
(EN)
Disclosed are methods for protecting a subject from harmful effects of ionizing radiation. The method includes administering to the subject an effective amount of at least one reduced folate. Also disclosed are radioprotective compositions that include a first radioprotective agent and a second radioprotective agent, where the first radioprotective agent is a reduced folate. Methods for protecting a subject from harmful effects of ultraviolet radiation are also disclosed.
(FR)
L'invention concerne des méthodes destinées à protéger un sujet contre les effets nuisibles d'un rayonnement ionisant. Cette méthode consiste à administrer à ce sujet une dose efficace d'au moins un folate réduit. L'invention concerne également des compositions radioprotectrices renfermant un premier agent radioprotecteur et un second agent radioprotecteur, le premier agent radioprotecteur étant un folate réduit. L'invention se rapporte en outre à des méthodes destinées à protéger un sujet contre les effets nuisibles d'un rayonnement ultraviolet.
Latest bibliographic data on file with the International Bureau