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1. (WO2007002325) PYRROLO[2,3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/002325 International Application No.: PCT/US2006/024361
Publication Date: 04.01.2007 International Filing Date: 21.06.2006
IPC:
C07D 471/04 (2006.01) ,A61K 31/435 (2006.01) ,C07C 49/517 (2006.01) ,A61P 35/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
49
Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
385
Saturated compounds containing a keto group being part of a ring
517
containing ether groups, groups, groups, or groups
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
PLEXXIKON, INC. [US/US]; 91 Bolivar Drive, Suite A Berkeley, CA 94710, US (AllExceptUS)
IBRAHIM, Prahbha, N. [US/US]; US (UsOnly)
ARTIS, Dean, R. [US/US]; US (UsOnly)
BREMER, Ryan [US/US]; US (UsOnly)
MAMO, Shumeye [US/US]; US (UsOnly)
NESPI, Marika [IT/US]; US (UsOnly)
ZHANG, Chao [CN/US]; US (UsOnly)
ZHANG, Jiazhong [CN/US]; US (UsOnly)
ZHU, Yong-Liang [CN/US]; US (UsOnly)
TSAI, James [US/US]; US (UsOnly)
HIRTH, Klaus-Peter [US/US]; US (UsOnly)
BOLLAG, Gideon [US/US]; US (UsOnly)
SPEVAK, Wayne [US/US]; US (UsOnly)
CHO, Hanna [US/US]; US (UsOnly)
GILLETTE, Samuel, J. [US/US]; US (UsOnly)
WU, Guoxiam [CN/US]; US (UsOnly)
ZHU, Hongyao [US/US]; US (UsOnly)
SHI, Shenghua [US/US]; US (UsOnly)
Inventors:
IBRAHIM, Prahbha, N.; US
ARTIS, Dean, R.; US
BREMER, Ryan; US
MAMO, Shumeye; US
NESPI, Marika; US
ZHANG, Chao; US
ZHANG, Jiazhong; US
ZHU, Yong-Liang; US
TSAI, James; US
HIRTH, Klaus-Peter; US
BOLLAG, Gideon; US
SPEVAK, Wayne; US
CHO, Hanna; US
GILLETTE, Samuel, J.; US
WU, Guoxiam; US
ZHU, Hongyao; US
SHI, Shenghua; US
Agent:
WARBURG, Richard, J. ; FOLEY & LARDNER LLP 11250 El Camino Real, Suite 200 San Diego, CA 92130, US
Priority Data:
60/692,96022.06.2005US
60/731,52828.10.2005US
Title (EN) PYRROLO[2,3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
(FR) COMPOSES ET METHODES DE MODULATION DE LA KINASE ET INSTRUCTIONS AFFERENTES
Abstract:
(EN) Compounds of formula III which are active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.
(FR) Composés actifs sur les protéines kinases, ainsi que méthodes d’utilisation de ces composés pour le traitement de pathologies et de symptômes associés à une activité aberrante des protéines kinases, y compris les kinases B-Raf, c- Raf-1, Fms, Jnkl, Jnk2, Jnk3 et Kit, ainsi que toutes mutations de celles-ci.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NO20076659MXMX/a/2007/016463KR1020080030619IL188248VN18298JP2008546797
RU0002418800CN101243084NZ565255VN24303ID049.3237IN4938/KOLNP/2007
EG27895