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1. (WO2007002300) NON-IN SITU HYBRIDIZATION METHOD FOR DETECTING CHROMOSOMAL ABNORMALITIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/002300    International Application No.:    PCT/US2006/024321
Publication Date: 04.01.2007 International Filing Date: 22.06.2006
IPC:
C12Q 1/68 (2006.01), C07H 21/04 (2006.01)
Applicants: QUEST DIAGNOSTICS INVESTMENTS INCORPORATED [US/US]; 300 Delaware Avenue, Wilmington, DC 19899 (US) (For All Designated States Except US).
ALBITAR, Maher [US/US]; (US) (For US Only).
CHAN, Huai-huang [US/US]; (US) (For US Only)
Inventors: ALBITAR, Maher; (US).
CHAN, Huai-huang; (US)
Agent: WARBURG, Richard, J.; FOLEY & LARDNER LLP, P.o. Box 80278, San Diego, CA 92138-0278 (US)
Priority Data:
11/165,445 23.06.2005 US
Title (EN) NON-IN SITU HYBRIDIZATION METHOD FOR DETECTING CHROMOSOMAL ABNORMALITIES
(FR) METHODE D'HYBRIDATION NON IN SITU DE DETECTION D'ANOMALIES CHROMOSOMIQUES
Abstract: front page image
(EN)The present invention provides methods of detecting chromosomal or genetic abnormalities associated with various diseases or with predisposition to various diseases. In particular, the present invention provides advanced methods of performing DNA hybridization, capture, and detection on solid support. Invention methods are useful for the detection, diagnosis, predicting response to therapy, detecting minimal residual disease, prognosis, or monitoring of disease treatment or progression of particular disease conditions such as cell proliferative disorders
(FR)L'invention porte sur des méthodes de détection d'anomalies chromosomiques ou génétiques associées à différentes maladies ou prédispositions à ces maladies, et en particulier sur des procédés avancés d'hybridation, de capture et de détection d'ADN sur supports solides. Lesdites méthodes s'avèrent utiles pour la détection, le diagnostic et la prédiction d'une réponse à une thérapie, la détection de maladies résiduelles minimes, et le pronostic ou le suivi du traitement ou de la progression d'états morbides particuliers, tels que des troubles de prolifération cellulaire.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)