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Machine translation
1. (WO2007002293) AZAINDAZOLE COMPOUNDS AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/002293    International Application No.:    PCT/US2006/024313
Publication Date: 04.01.2007 International Filing Date: 22.06.2006
IPC:
A61K 31/496 (2006.01), C07D 487/06 (2006.01)
Applicants: CHEMOCENTRYX, INC. [US/US]; 850 Maude Ave., Mountain View, California 94043 (US) (For All Designated States Except US).
ZHANG, Penglie [CN/US]; (US) (For US Only).
PENNELL, Andrew M. K. [GB/US]; (US) (For US Only).
WRIGHT, John J. Kim [AU/US]; (US) (For US Only).
CHEN, Wei [CN/US]; (US) (For US Only).
LELETI, Manmohan R. [IN/US]; (US) (For US Only).
LI, Yandong [CN/US]; (US) (For US Only).
LI, Lianfa [CN/US]; (US) (For US Only).
XU, Yuan [CN/US]; (US) (For US Only)
Inventors: ZHANG, Penglie; (US).
PENNELL, Andrew M. K.; (US).
WRIGHT, John J. Kim; (US).
CHEN, Wei; (US).
LELETI, Manmohan R.; (US).
LI, Yandong; (US).
LI, Lianfa; (US).
XU, Yuan; (US)
Agent: KEZER, William B.; Townsend And Townsend And Crew Llp, Two Embarcadero Center, 8th Floor, San Francisco, California 94111 (US)
Priority Data:
60/693,525 22.06.2005 US
Title (EN) AZAINDAZOLE COMPOUNDS AND METHODS OF USE
(FR) COMPOSES D'AZAINDAZOLE ET METHODES D'UTILISATION DESDITS COMPOSES
Abstract: front page image
(EN)Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
(FR)Composés qui agissent en tant qu'antagonistes puissants du récepteur CCR1 et possèdent une activité anti-inflammatoire in vivo. Lesdits composés sont généralement des dérivés d'aryle pipérazine et sont utiles dans des compositions pharmaceutiques, dans des méthodes de traitement de maladies médiées par CCR1, et en tant que témoins dans des analyses pour l'identification d'antagonistes compétitifs de CCR1.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)